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Pociredir for Sickle Cell Disease

Enrolling by invitation at 7 trial locations
CC
Overseen ByCall Center
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Fulcrum Therapeutics
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This is an open-label study to evaluate the safety and tolerability of long-term treatment with pociredir without a comparator in participants with SCD who have previously been treated and shown benefit with pociredir in feeder study 6058-SCD-101 (NCT05169580). Participants in this study will receive once daily doses of pociredir for up to 48 months.

Are You a Good Fit for This Trial?

Inclusion Criteria

I am over 18 and completed Study 6058-SCD-101.
I have signed the consent form and can follow the study rules.
I meet all other required criteria for the study.

What Are the Treatments Tested in This Trial?

Interventions

  • Pociredir

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: PociredirExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Fulcrum Therapeutics

Lead Sponsor

Trials
8
Recruited
680+
Headquarters
Cambridge, United States

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