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Behavioral Intervention for Opioid Use Disorder (HOPE MOUD Trial)

Phase 2 & 3
Recruiting
Research Sponsored by University of California, Irvine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Is not currently prescribed MOUD
English speakers only
Timeline
Screening 3 weeks
Treatment Varies
Follow Up request during the course of the 12-week community
Awards & highlights

HOPE MOUD Trial Summary

This trial is testing an intervention to get people with opioid addiction to use medication-assisted treatment, and will follow up with them for 1 year.

Who is the study for?
This trial is for adults over 18 living in CA, NV, AZ, OR, WA with moderate to severe opioid use disorder who use social media at least twice a week. Participants must speak English and be willing to create or have a Facebook/social media account to engage with the study's online support group.Check my eligibility
What is being tested?
The HOPE intervention is being tested for its effectiveness in encouraging patients with opioid use disorder to start taking medications designed to treat their condition. The study will follow participants for up to one year and analyze data from an online community.See study design
What are the potential side effects?
Since this trial involves a behavioral intervention rather than medication, traditional side effects are not expected. However, participants may experience emotional or psychological responses due to engagement with the online support program.

HOPE MOUD Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am not currently taking medication for opioid use disorder.
Select...
I speak English.
Select...
I am 18 years old or older.

HOPE MOUD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~request during the course of the 12-week community
This trial's timeline: 3 weeks for screening, Varies for treatment, and request during the course of the 12-week community for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of requests to receive a resource on medications that can be used to treat opioid use disorder

Side effects data

From 2013 Phase 1 & 2 trial • 16 Patients • NCT01923896
13%
Diarrhea
100%
80%
60%
40%
20%
0%
Study treatment Arm
Behavioral Intervention & DCS
Behavioral Intervention & Placebo

HOPE MOUD Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
HOPE intervention peer-led online community
Group II: ControlActive Control1 Intervention
Online community without HOPE intervention psychological components

Find a Location

Who is running the clinical trial?

University of California, IrvineLead Sponsor
544 Previous Clinical Trials
1,922,403 Total Patients Enrolled

Media Library

HOPE Online Support Intervention Clinical Trial Eligibility Overview. Trial Name: NCT04712981 — Phase 2 & 3
Opioid Use Disorder Research Study Groups: Intervention, Control
Opioid Use Disorder Clinical Trial 2023: HOPE Online Support Intervention Highlights & Side Effects. Trial Name: NCT04712981 — Phase 2 & 3
HOPE Online Support Intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT04712981 — Phase 2 & 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we able to sign patients up for this trial at the moment?

"The clinical trial is still actively recruiting patients, as of 5/16/2022. The study was first posted on 4/23/2020 and is looking for 640 individuals from 1 medical site."

Answered by AI

How many people are enrolled in this clinical trial?

"Correct, the information on clinicaltrials.gov indicates that this trial is recruiting patients at present. This trial was first posted on 4/23/2020 and last updated on 5/16/2022. The study is looking for 640 participants across 1 location."

Answered by AI

Who else is applying?

What site did they apply to?
University of California, Irvine
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
2

What questions have other patients asked about this trial?

How often do I go to Irvine?
PatientReceived 2+ prior treatments

Why did patients apply to this trial?

I am currently going through withdrawals from Butrans.
PatientReceived 1 prior treatment
Recent research and studies
clinicaltrials.govStudy
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder
Sean D Young 2021. "Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04712981.
All > Opioid Dependence
~179 spots leftby Jul 2025
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