Your session is about to expire
← Back to Search
Tadalafil for Duchenne Muscular Dystrophy
Study Summary
This trial will study how well a common vasodilator drug works in boys with Duchenne muscular dystrophy. The findings could help inform a longer-term intervention study to see if the drug can help slow disease progression in DMD.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2017 Phase 4 trial • 635 Patients • NCT02224846Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I have been diagnosed with DMD based on my early symptoms, physical exams, high creatine kinase levels, and specific tests showing lack of dystrophin.I am older than 13 years.I have medical conditions that are not well-controlled.I have a condition affecting my muscles, like myasthenia gravis.I am not taking nitrates, alpha-blockers, or other PDE5 inhibitors.I have been diagnosed with DMD based on my symptoms, tests, and genetic confirmation.I can walk on my own without help.I am at least 7 years old.I have been diagnosed with DMD based on my symptoms, tests, and genetic confirmation.I am at least 7 years old.I am at least 7 years old.I can walk on my own without help.I can walk on my own without help.
- Group 1: Tadalafil plus BOLD-MRI (Schedule A)
- Group 2: Tadalafil plus Doppler ultrasound (Schedule B)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many individuals are included in this clinical trial?
"That is correct, the online clinicaltrial.gov registry reflects that this study is still recruiting patients. The posting date was December 14th, 2021 and the most recent update was on November 8th, 2022. They are looking for a total of 25 participants at 1 location."
Are researchers actively searching for test subjects?
"The trial, which was created on December 14th 2021 according to clinicaltrials.gov, is still recruiting patients as of November 8th 2022."
Does this experimental treatment only test on people over the age of 50?
"Children that meet the age criteria of 7 to 13 years old are eligible for this study. In total, there are 61 trials underway involving patients under 18 and 50 for those over 65."
Who meets the qualifications to participate in this clinical trial?
"In this particular study, researchers are only recruiting 25 patients that have muscular dystrophy (duchenne) and fall between the ages of 7-13. Most importantly, these individuals must meet the following clinical requirements: A diagnosis of DMD confirmed by 1) clinical history with features before the age of five, 2) physical examination, 3) elevated serum creatine kinase level and 4) absence of dystrophin expression, as determined by immunostaining or Western blot (<2%) and/or DNA confirmation of dystrophin mutation., a minimum entry age into the trial of 7.0 years old, and be ambul"
Who else is applying?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
What state do they live in?
How responsive is this trial?
Typically responds via
Share this study with friends
Copy Link
Messenger