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Sacubitril-Valsartan for High Blood Pressure (PRECISION-BP Trial)
PRECISION-BP Trial Summary
This trial seeks to find a way to lower the risk of cardiovascular events for obese individuals by specifically targeting the natriuretic peptides to control blood pressure.
PRECISION-BP Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPRECISION-BP Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PRECISION-BP Trial Design
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Logistics
Other reimbursement is provided
Other forms of reimbursement are provided for this trial.
Who is running the clinical trial?
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- I am 18 years old or older.My BMI is either below 30 or above 45.You have a history of angioedema (swelling of the skin and tissues beneath the skin).You have a serious mental health condition.I have a history of high blood pressure in the lungs.I am not pregnant, breastfeeding, and I use effective birth control or practice abstinence.You have a body mass index (BMI) between 30 and 45.I am under 18 years old.My kidney function is reduced, and I have protein in my urine.I am on the highest doses of 3 or more blood pressure medicines.I have a history of heart disease, stroke, diabetes, or seizures.
- Group 1: Sacubitril/Valsartan Morning Dose
- Group 2: Sacubitril/Valsartan Evening Dose
- Group 3: Valsartan Morning Dose
- Group 4: Valsartan Evening Dose
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: You will receive the treatment for 3 null
- Follow Ups: You may be asked to continue sharing information regarding the trial for 3 Months after you stop receiving the treatment.
Frequently Asked Questions
Are we still looking for more participants for this experiment?
"The trial is still recruiting patients, according to the clinicaltrials.gov listing. The posting went up on February 18th, 2022 and was edited as recently as October 14th of the same year."
Are there any other ongoing research projects studying Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet?
"There are currently 39 ongoing clinical trials studying the efficacy of Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet. Of those, 8 are large Phase 3 trials. The majority of these studies are taking place in Montreal, Quebec; however, there are a total of 812 research sites worldwide."
What is the therapeutic target for Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet?
"The ventricular dysfunction, left can often be treated by taking Sacubitril-Valsartan 49 Mg-51 Mg Oral Tablet. This medication is also able to help patients that are struggling with essential hypertension or have a history of cardiovascular events."
How many people are being enrolled in this clinical trial?
"You are correct, the trial is still recruiting patients. The information on clinicaltrials.gov shows that the trial was posted on 2/18/2022 and updated on 10/14/2022. Currently, they are looking to enroll 160 patients from 1 location."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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