The Brain Health PRO Online Risk Factor Reduction Study to Prevent Dementia

(BHPROOF Trial)

Overseen By Pennny Slack, MSc

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of British Columbia

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

What You Need to Know Before You Apply

What is the purpose of this trial?

This study will recruit participants at risk for dementia to participate in an online educational program called Brain Health PRO (BHPro). The BHPro intervention is designed to address modifiable risk factors for dementia through a 6-month, fully online, educational program conveying the best available evidence for lifestyle changes that can mitigate dementia risk, and foster engagement toward one's own brain health. Achieving lifestyle changes in a diverse Canadian population through online education would be a major achievement in dementia prevention in Canada, with widespread personal and socioeconomic benefits.

Eligible participants will be randomly assigned to either start Brain Health PRO immediately or in 6 months (delayed-start control group). All participants will have the opportunity to have access to BHPro for 6 months during the course of the study and will have open access to all content for 12 months following the initial 6-month intervention. Participation will last from 18-24 months depending on group assignment.

Are You a Good Fit for This Trial?

Inclusion Criteria

* Completion and documentation of the electronic Informed Consent Process (from the participant)

* Sufficient proficiency in English or French to undergo online assessments and participate in an online educational program.

* Technical ability to participate in an online educational program and remote assessments (i.e., regularly have access to a computer or tablet with an internet connection; have access to a desktop or laptop computer with an internet connection at least once every 6 months; ability to send and receive emails; ability to complete online assessments)

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

Group I: Immediate BHPro Intervention Group Experimental Treatment 1 Intervention

Participants in this group will start Brain Health PRO immediately at baseline

Group II: Delayed Start BHPro Experimental Treatment 1 Intervention

Participants in this group will start Brain Health PRO in 6 months (delayed)

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials

1,506

Recruited

2,528,000+

Canadian Institutes of Health Research (CIHR)

Collaborator

Trials

1,417

Recruited

26,550,000+

Alzheimer Society of Canada

Collaborator

Trials

10

Recruited

2,900+

Baycrest

Collaborator

Trials

46

Recruited

6,900+

The Canadian Consortium on Neurodegeneration in Aging (CCNA)

Collaborator