Exercise Testing for Cardiorespiratory Fitness Evaluation
(POPE Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will compare the measured oxygen consumption (VO2) obtained during sub-maximal exercise testing with the estimated VO2 derived from a non-exercise questionnaire.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
Is exercise testing safe for humans?
How is exercise testing for cardiorespiratory fitness different from other treatments?
Exercise testing is unique because it is a noninvasive method that evaluates cardiovascular function during physical activity, helping to tailor exercise programs for individual health needs. Unlike other treatments, it provides insights into both aerobic and anaerobic metabolism, which can guide personalized fitness and rehabilitation plans.678910
What data supports the effectiveness of the treatment Exercise, Physical Activity, Workout, Fitness Training?
Research shows that exercise programs are beneficial for patients with heart failure, improving their quality of life and being an essential part of cardiac rehabilitation. Additionally, exercise testing helps evaluate and improve cardiorespiratory fitness, which is important for managing cardiovascular and pulmonary diseases.1112131415
Who Is on the Research Team?
David MacLeod, FRCA
Principal Investigator
Duke University
Are You a Good Fit for This Trial?
This trial is for English-speaking adults who can walk (with or without help) and are patients at the Preoperative Anesthesia and Surgical Screening clinic with a low fitness score. They must be able to consent. Those with severe heart issues, very high blood pressure, recent heart attacks, or dementia cannot join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Preoperative Assessment
Participants complete the Duke Activity Status Index (DASI) questionnaire and, if eligible, undergo a sub-maximal exercise test (6MST) to measure VO2.
Follow-up
Participants are monitored for safety and effectiveness after the preoperative assessment
What Are the Treatments Tested in This Trial?
Interventions
- Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor