TRX103 for Uveitis

(PEACOCX Trial)

PS
Overseen ByPEACOCX Study Team
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this Phase 1, first in uveitis open-label study is to assess the safety and tolerability of TRX-103 in patients with non infectious uveitis (NIU). It is anticipated that up to 18 Subjects will be enrolled during a 18-24 month enrollment period. TRX-103 will be infused one time.

Who Is on the Research Team?

QN

Quan Nguyen, MD

Principal Investigator

Stanford University

Are You a Good Fit for This Trial?

Inclusion Criteria

I am between 18 and 70 years old.
I weigh at least 40 kilograms.
2. Have been on a stable dose for at least 7 days prior to TRX103 dose.
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a one-time infusion of TRX-103 followed by observation

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

52 weeks
Multiple visits at 3-month, 6-month, and 1-year

What Are the Treatments Tested in This Trial?

Interventions

  • TRX103

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: TRX-103 OutpatientExperimental Treatment1 Intervention
Group II: TRX-103 InpatientExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Quan Dong Nguyen

Lead Sponsor

Trials
3
Recruited
70+