20 Participants Needed

Psilocybin for Stroke

(PHATHOM Trial)

SR
Overseen BySteven R Zeiler, M.D., Ph.D.
Age: 18+
Sex: Any
Trial Phase: Phase 1
Sponsor: Johns Hopkins University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The main purpose of the current studies is to evaluate the safety and tolerability of psilocybin in patients with chronic stroke.

Who Is on the Research Team?

VU

Victor Urrutia, M.D.

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

This trial is for adults over 18 who had a stroke confirmed by CT or MRI at least a year ago. Participants must understand the study, agree not to start new meds without approval, avoid certain supplements and nonprescription drugs, follow dietary restrictions before dosing, have transportation arranged post-treatment, and provide emergency contact details.

Inclusion Criteria

I am over 18 years old.
I have taken a pregnancy test and it is negative.
I had a stroke confirmed by a scan more than a year ago.
See 7 more

What Are the Treatments Tested in This Trial?

Interventions

  • Psilocybin

Trial Overview

The trial is testing the safety and tolerability of psilocybin from Usona Institute in patients with chronic stroke. It aims to see how well these individuals can handle the drug as an adjunct therapy alongside their standard treatment regimen.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: 25 mg of psilocybinExperimental Treatment1 Intervention
Group II: 12.5 mg + 12.5 mg of psilocybinExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins University

Lead Sponsor

Trials
2,366
Recruited
15,160,000+

Rose Hill

Collaborator

Usona Institute

Collaborator

Trials
18
Recruited
1,100+

University of California, Berkeley

Collaborator

Trials
193
Recruited
716,000+