Varegacestat for Healthy Subjects
What You Need to Know Before You Apply
What is the purpose of this trial?
This clinical study is designed to study the effect of a single dose of varegacestat on cardiac repolarization in healthy adult participants.
Will I have to stop taking my current medications?
The trial information does not specify if you need to stop taking your current medications. However, if you have taken an investigational drug recently, you may not be eligible to participate.
Are You a Good Fit for This Trial?
This trial is for healthy adults, both male and female (females must be of non-childbearing potential), aged 18 to 55. Participants should have no significant medical history or conditions that could affect the study results or increase risk.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single dose of varegacestat, placebo, or moxifloxacin in a 3-way crossover design. Cardiodynamic ECGs and PK samples are collected.
Washout
A washout period of at least 14 days between each treatment dose to clear the previous treatment from the body.
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Varegacestat
Find a Clinic Near You
Who Is Running the Clinical Trial?
Immunome, Inc.
Lead Sponsor