78 Participants Needed

MT-701 for Safety Evaluation in Healthy Subjects

TN
Overseen ByToll-Free Number
Age: 18 - 65
Sex: Any
Trial Phase: Phase 1
Sponsor: Mirador Therapeutics, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

First-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of single and multiple doses of MT-701 in healthy participants.

Are You a Good Fit for This Trial?

This trial is for healthy adults aged 19-55 who can consent to study requirements. Women must be unable to bear children, either postmenopausal or surgically sterile with documentation. Men should use effective contraception during the study.

Inclusion Criteria

I am in good overall health.
I can sign and understand the consent form and follow the study's requirements.
I am between 19 and 55 years old and cannot become pregnant.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Single Ascending Dose

Participants receive a single intravenous/subcutaneous dose of MT-701 to assess safety and tolerability

1 week

Multiple Ascending Dose

Participants receive multiple intravenous/subcutaneous doses of MT-701 to assess safety and tolerability

4 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

2 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • MT-701

Trial Overview

The trial tests MT-701's safety and how it affects the body (pharmacokinetics) in single and multiple doses on healthy people. It also checks if the body creates any immune response against MT-701.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Part 2- Multiple Ascending DoseExperimental Treatment1 Intervention
Group II: Part 1- Single Ascending DoseExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mirador Therapeutics, Inc.

Lead Sponsor

Trials
1
Recruited
100+