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Vorinostat + Azacitidine for Head and Neck Cancers
Study Summary
This trial is studying vorinostat and azacitidine to see how well they work in treating patients with nasopharyngeal cancer or nasal natural killer T-cell lymphoma.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My cancer has come back in the same area but cannot be treated with radiation to cure it.I do not have any serious illnesses or social situations that would stop me from following the study's requirements.I have cancer that has spread or returned and was treated with chemotherapy after it came back.I can take care of myself but might not be able to do heavy physical work.I do not have chronic active hepatitis B.I am not pregnant and will use birth control during the study.I haven't taken sodium valproate in the last 2 weeks.My kidney function, measured by creatinine levels, is within normal limits.You are expected to live for at least 6 more months.I have been diagnosed with a specific type of throat or nasal cancer.My cancer has spread and cannot be removed with surgery.I am not HIV-positive or not on anti-retroviral therapy.You have had allergic reactions to drugs that are similar to 5AC or SAHA.I haven't had chemotherapy or radiotherapy in the last 4 weeks and have recovered from any side effects.I do not have cancer spread to my brain or its coverings but may have it at the base of my skull.
- Group 1: Treatment (azacitidine, vorinostat)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is enrollment still open for this medical experiment?
"The clinical trial listed on clinicaltrials.gov is no longer recruiting new participants; the posting dates are March 3rd 2006 and June 28th 2022 respectively. Nevertheless, there are 5160 other trials actively seeking participants across a variety of medical fields."
What prior research has been done to assess the efficacy of Pharmacological Study?
"Currently, 202 active trials in regards to Pharmacological Study have been launched and 34 of those are now at Phase 3. The majority of these studies are conducted out of Saint Louis, Missouri yet there is an expansive network containing 6157 different locations researching the same topic."
Has the Pharmacological Study achieved regulatory approval from the FDA?
"Power's research team assigned a rating of 1 for the safety of this pharmacological study, as it is still in its preliminary stages and has minimal data backing up its efficacy."
What is the upper limit on participants for this experiment?
"As of June 28th, 2022 this trial is no longer accepting patients. It had been initially posted on March 3rd, 2006 and was last edited recently. If you are considering other studies there are 4958 carcinoma or squamous cell clinical trials actively recruiting as well 202 Pharmacological Study trials welcoming participants."
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