Hyperpolarized xenon MRI for Non-Small Cell Lung Cancer

Hospital of the University of Pennsylvania, Philadelphia, PA
Non-Small Cell Lung CancerHyperpolarized xenon MRI - CombinationProduct
Eligibility
18 - 85
All Sexes
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Study Summary

This trial is testing a new way to map out cancer radiation treatment plans that could reduce risk or severity of radiation pneumonitis.

Treatment Effectiveness

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: One year.

One year.
Number of patients reporting one or more adverse events related to hyperpolarized xenon inhalation in this population.
Number of patients with radiation therapy related adverse events as assessed by CTCAE v4.0.

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

2 Treatment Groups

Standard-of-care Radiation Therapy for lung cancer using HXe MRI for diagnosis.
1 of 2
Guided Radiation Therapy for lung cancer using HXe MRI for functional lung avoid...
1 of 2

Experimental Treatment

20 Total Participants · 2 Treatment Groups

Primary Treatment: Hyperpolarized xenon MRI · No Placebo Group · Phase 1

Standard-of-care Radiation Therapy for lung cancer using HXe MRI for diagnosis.
CombinationProduct
Experimental Group · 1 Intervention: Hyperpolarized xenon MRI · Intervention Types: CombinationProduct
Guided Radiation Therapy for lung cancer using HXe MRI for functional lung avoidance and diagnosis.
CombinationProduct
Experimental Group · 1 Intervention: Hyperpolarized xenon MRI · Intervention Types: CombinationProduct

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: one year.

Who is running the clinical trial?

Xemed LLCLead Sponsor
7 Previous Clinical Trials
293 Total Patients Enrolled
University of PennsylvaniaOTHER
1,896 Previous Clinical Trials
41,212,903 Total Patients Enrolled

Eligibility Criteria

Age 18 - 85 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
If you have lung cancer and are also receiving radiation therapy, you will be excluded if you have other lung-related health issues like COPD stage 3+.

Frequently Asked Questions

Are participants still welcome to join this clinical investigation?

"Correct. Records on clinicaltrials.gov attest to the fact that this medical trial, which was first posted on March 17th 2022, is actively seeking participants. To date, 20 individuals are required from a single site." - Anonymous Online Contributor

Unverified Answer

What is the ideal demographic of individuals to be involved in this research?

"This trial is seeking 20 individuals with non-small cell lung carcinoma between 18 and 85. The primary criteria for eligibility include having a diagnosis of non-small cell lung cancer, planning to receive radiation therapy, or being diagnosed with de novo lung cancer while also exhibiting natural co morbidities such as COPD stage 3+. It is preferred that participants have had successful radiation treatment in the past for a prior case of lung cancer." - Anonymous Online Contributor

Unverified Answer

Has the FDA approved Hyperpolarized xenon MRI for medical use?

"The safety of Hyperpolarized xenon MRI is assessed as a 1 on the scale, given that this is an initial Phase 1 trial with scant data available to evaluate its efficacy and security." - Anonymous Online Contributor

Unverified Answer

How many participants are involved in the current research endeavor?

"Yes, the information on clinicaltrials.gov attests that this medical trial is currently recruiting patients. This research was first posted on March 17th 2022 and has since been modified as of March 29th 2022. The study requires 20 individuals to be recruited from one centre." - Anonymous Online Contributor

Unverified Answer

Is eligibility for this experiment restricted to those under 45 years of age?

"According to the eligibility criteria for this trial, participants must fall between 18 and 85 years old. The medical landscape is vast with 21 clinical trials available specifically targeting those under 18 and 1360 trails open to patients above 65." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.