Azer-cel for Autoimmune Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
The main objective of the study is to determine the recommended phase 2 dose (RP2D) of Azercabtagene zapreleucel (azer-cel).
Will I have to stop taking my current medications?
Yes, you will need to stop taking your current disease modifying therapy (DMT) before joining the trial, and there is a specific washout period (time without taking certain medications) required before receiving treatment.
Are You a Good Fit for This Trial?
This trial is for individuals with progressive forms of Multiple Sclerosis, including Primary Progressive and Secondary Progressive MS. Participants must have stopped any disease modifying therapy before joining the study and meet specific criteria for medication washout.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a single dose of intravenous (IV) infusion of azer-cel at different dose levels
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Azercabtagene zapreleucel (azer-cel)
Find a Clinic Near You
Who Is Running the Clinical Trial?
TG Therapeutics, Inc.
Lead Sponsor