Radiation to Treat Joint Damage Caused by Cancer Immunotherapy
CT
Overseen ByClinical Trials Intake
Age: 18+
Sex: Any
Trial Phase: Phase 1
Sponsor: University of Chicago
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
What You Need to Know Before You Apply
What is the purpose of this trial?
This study will prospectively investigate the feasibility and safety of administering LDRT in patients with immunotherapy-induced inflammatory arthritis.
Who Is on the Research Team?
PR
Pankti Reid
Principal Investigator
University of Chicago
Are You a Good Fit for This Trial?
Inclusion Criteria
* Patients must have histologically confirmed malignancy that is metastatic or unresectable and for which they are receiving single agent or combination immunotherapy or within the last 6 months.
* Rheumatologist-established diagnosis of new onset CTCAE grade 2-3 immunotherapy-induced inflammatory arthritis or activated osteoarthritis, involving one or more joints (up to 3) including but not limited to hands, shoulders, elbows, hips, knees and ankles.
* Age ≥ 40 years.
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What Are the Treatments Tested in This Trial?
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Group I: Radiation treatmentExperimental Treatment1 Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Chicago
Lead Sponsor
Trials
1,086
Recruited
844,000+
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