40 Participants Needed

Patient-Specific Predictions for Post-Knee Replacement Satisfaction

(SensorRCT Trial)

LS
BL
Overseen ByBrent Lanting
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: London Health Sciences Centre OR Lawson Research Institute of St. Joseph's
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

More than 70,000 total knee replacement procedures are performed annually in Canada, representing a growth of 17% over the past 5 years, with further increases anticipated due to an aging population. While total knee replacement offers improved quality of life for patients and is cost effective for the healthcare system, 20% of patients routinely report dissatisfaction with the procedure. Patient dissatisfaction has been strongly linked to unmet expectations of outcomes after the surgery, especially with respect to physical activity. Counselling patients on appropriate expectations has been suggested as a means to improve satisfaction. Recently, our group has developed a tool to predict the functional ability of an individual patient after total knee replacement. This tool employs machine learning to classify patients as more likely to maintain or improve function, based on a functional test performed in clinic while wearing a sensor system around each knee. Implementing this tool in clinic pre-operatively could assist in setting appropriate expectations for each patient. Our primary objective is to compare patient satisfaction scores at one year after total knee replacement in patients who were informed of their specific expected functional outcome compared to patients who were not informed of their predicted functional outcome. We hypothesize that patients who are given an informed expectation will have higher satisfaction scores. This in turn may decrease health system costs associated with additional clinic visits from dissatisfied patients.

Research Team

Search | St. Joseph's Health Care London

Brent Lanting, MD

Principal Investigator

Lawson Health Science Centre

Eligibility Criteria

This trial is for patients with osteoarthritis who are scheduled for a primary total knee replacement. It's not suitable for those getting both knees replaced at once, individuals who can't read, write or speak English, or have conditions affecting their walk or previous knee surgeries.

Inclusion Criteria

I am scheduled for a first-time knee replacement due to osteoarthritis.

Exclusion Criteria

I have a history of inflammatory arthritis.
I have a muscle or nerve condition that affects my ability to walk.
I am scheduled for surgery to replace both of my knees.
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Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Pre-operative Assessment

Participants undergo pre-operative assessments including functional tests with a sensor system to set expectations

1-2 weeks
1 visit (in-person)

Surgery and Immediate Post-operative Care

Participants undergo total knee replacement surgery and receive immediate post-operative care

1 week
In-patient stay

Follow-up

Participants are monitored for safety and effectiveness after surgery, including assessments at 2 weeks, 6 weeks, 3 months, and 1 year post-operation

1 year
Multiple visits (in-person and virtual)

Treatment Details

Interventions

  • Patient-Specific Prediction of Functional Outcome
  • Standard Pre-Operative Total Knee Arthroplasty Information
Trial OverviewThe study tests if knowing the predicted outcome of knee surgery improves patient satisfaction. One group will receive standard pre-op info while the other will also get predictions on their post-surgery function based on a sensor test and machine learning.
Participant Groups
2Treatment groups
Experimental Treatment
Group I: Standard Care GroupExperimental Treatment1 Intervention
Standard Pre-Operative Total Knee Arthroplasty Information
Group II: Outcome Prediction GroupExperimental Treatment2 Interventions
Patient-Specific Prediction of Functional Outcome and Standard Pre-Operative Total Knee Arthroplasty Information

Find a Clinic Near You

Who Is Running the Clinical Trial?

London Health Sciences Centre OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
668
Recruited
424,000+

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
678
Recruited
421,000+

London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's

Lead Sponsor

Trials
686
Recruited
427,000+

Lawson Health Research Institute

Lead Sponsor

Trials
684
Recruited
432,000+