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Broccoli Sprouts for Healthy Eating

N/A
Waitlist Available
Led By Emily Ho, PhD
Research Sponsored by Oregon State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy men and women, 18-60 years of age
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 3, 6, 24, 48 and 72 hours after consuming a single serving of sprouts
Awards & highlights

Study Summary

This trial will study the effects of broccoli sprouts on the human body at a molecular and metabolic level. It will also look at the composition of the microbiome (the microorganisms that live in the gut).

Who is the study for?
This trial is for healthy men and women aged 18-60 who don't smoke or use tobacco, aren't pregnant, and haven't used antibiotics in the past 6 months. Participants must avoid certain foods and supplements before and during the study, have a BMI between 18.5 to 30, not exercise vigorously over 7 hours weekly, and be free of significant health issues.Check my eligibility
What is being tested?
The study investigates how eating broccoli sprouts affects molecular profiles in blood, urine, and gut bacteria composition. It involves consuming either regular or specially labelled alfalfa or broccoli sprouts to track changes.See study design
What are the potential side effects?
Since this trial involves eating common vegetables (broccoli & alfalfa sprouts), side effects are expected to be minimal but could include digestive discomfort due to dietary changes.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 60 years old and in good health.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 3, 6, 24, 48 and 72 hours after consuming a single serving of sprouts
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3, 6, 24, 48 and 72 hours after consuming a single serving of sprouts for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Plasma sulforaphane
Plasma sulforaphane metabolites
Stool sample based gut microbiome composition using 16S rRNA gene sequencing
+2 more

Trial Design

4Treatment groups
Active Control
Placebo Group
Group I: Broccoli sproutsActive Control1 Intervention
Subjects will consume one serving (about 1 cup) of broccoli sprouts with breakfast (bagel, cream cheese, and orange juice).
Group II: Deuterium oxide-labeled broccoli sproutsActive Control1 Intervention
Subjects will consume one serving (about 1 cup) of deuterium oxide-labeled broccoli sprouts with breakfast (bagel, cream cheese, and orange juice).
Group III: Deuterium oxide-labeled alfalfa sproutsPlacebo Group1 Intervention
Subjects will consume one serving (about 1 cup) of deuterium oxide-labeled alfalfa sprouts with breakfast (bagel, cream cheese, and orange juice).
Group IV: Alfalfa sproutsPlacebo Group1 Intervention
Subjects will consume one serving (about 1 cup) of alfalfa sprouts with breakfast (bagel, cream cheese, and orange juice).

Find a Location

Who is running the clinical trial?

Oregon State UniversityLead Sponsor
50 Previous Clinical Trials
8,358 Total Patients Enrolled
United States Department of Agriculture (USDA)FED
97 Previous Clinical Trials
350,675 Total Patients Enrolled
Emily Ho, PhDPrincipal InvestigatorOregon State University

Media Library

Alfalfa sprouts (Other) Clinical Trial Eligibility Overview. Trial Name: NCT04641026 — N/A
Healthy Eating Research Study Groups: Broccoli sprouts, Deuterium oxide-labeled broccoli sprouts, Deuterium oxide-labeled alfalfa sprouts, Alfalfa sprouts
Healthy Eating Clinical Trial 2023: Alfalfa sprouts Highlights & Side Effects. Trial Name: NCT04641026 — N/A
Alfalfa sprouts (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04641026 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research permit enrolment of individuals aged 45 or older?

"This medical trial is open to patients aged 18-60. There are 13 separate trials available for minors and 36 studies available for seniors over 65 years of age."

Answered by AI

Is there still potential for participants to join this research initiative?

"Clinicaltrials.gov states that this trial has already finished enrollment, as the study was originally posted on February 22nd 2021 and last updated September 22nd 2022. Nevertheless, there are still 66 other studies currently looking for participants to join their trials."

Answered by AI

Do I satisfy the criteria to be included in this medical experiment?

"This trial is accepting 83 participants of age 18 - 60 that adhere to a healthy diet. Eligible candidates must be willing to abstain from herbal and phytochemical supplements, cruciferous vegetables, probiotic supplement intake for the week prior and during the study, while also completing a 10-day food diary. Additionally, they must give written informed consent in order to participate."

Answered by AI

Who else is applying?

What state do they live in?
Oregon
How old are they?
18 - 65
What site did they apply to?
Oregon State University
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Discovery of Biological Signatures for Cruciferous Vegetable Intake (Single Serving)
Emily Ho 2021. "Discovery of Biological Signatures for Cruciferous Vegetable Intake (Single Serving)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04641026.
All > Microbiome
~20 spots leftby Jun 2025
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