Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance
(Ang2 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
A study to see whether a medication called Angiotensin II works better than the routinely used medication to raise blood pressure in people with liver disease who are experiencing a serious drop in blood pressure.
The investigators want to find out if Angiotensin II can help the heart and blood vessels work together more effectively than standard treatments.
Who Is on the Research Team?
Siddharth Dugar, M.D.
Principal Investigator
The Cleveland Clinic
Are You a Good Fit for This Trial?
Inclusion Criteria
What Are the Treatments Tested in This Trial?
How Is the Trial Designed?
2
Treatment groups
Active Control
Angiotensin II will be continued for 24 hours and then discontinued, and SOC vasopressors resumed according to institutional practices.
Fixed-dose vasopressin and standard of care vasopressors increased as per institutional guidelines according to MAP targets.
Find a Clinic Near You
Who Is Running the Clinical Trial?
The Cleveland Clinic
Lead Sponsor
Innoviva Specialty Therapeutics
Industry Sponsor
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