Aspirin for Preeclampsia

LM
CA
Overseen ByChristina A. Penfield, MD, MPH
Age: 18 - 65
Sex: Female
Trial Phase: Phase < 1
Sponsor: NYU Langone Health
Must be taking: Aspirin
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is assess platelet phenotypes based on aspirin dosing in pregnant patients at risk for the development preeclampsia who are taking 81mg twice a day aspirin. Blood samples will be collected approximately 4 weeks after initiation of aspirin to evaluate the platelet phenotype during pregnancy in patients.

Who Is on the Research Team?

CA

Christina A. Penfield, MD, MPH

Principal Investigator

NYU Langone Health

Are You a Good Fit for This Trial?

Inclusion Criteria

Singleton viable gestation
Pregnant patients at high risk of preeclampsia: Patients meeting USPSTF recommendation for aspirin prophylaxis for preeclampsia based on clinical risk factors.
Pregnant people prior to 17 weeks
See 2 more

Exclusion Criteria

Undergoing glucose challenge test (GCT) at time of blood draw
Allergy or intolerance to aspirin
I am currently taking blood thinners or antiplatelet medication.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants take 81mg Aspirin orally, twice daily for 4 weeks

4 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Aspirin

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Twice daily dosing of AspirinExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

NYU Langone Health

Lead Sponsor

Trials
1,431
Recruited
838,000+