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Antiplatelet Agent

aspirin for Prophylaxis of Preeclampsia

Q: Does the eligibility criterion for this experiment encompass citizens above 25 years of age?

This study is recruiting adults aged 18-50.

Q: Who is eligible to join this medical experiment?

The eligible age range for this clinical trial is between 18 and 50. As a requirement, applicants must have preeclampsia prophylaxis. 40 individuals are needed to complete the study's cohort.

Q: What is the maximal number of participants enrolled in this clinical investigation?

Affirmative. Clinicaltrials.gov has information indicating that this clinical trial, which was inaugurated on the 1st of November 2023, is currently enrolling participants. 40 individuals from a single medical facility are necessary for successful recruitment.

Q: Does enrollment for this clinical trial remain open?

Affirmative. The most recent version of the information on clinicaltrials.gov shows that this trial is actively seeking out participants; it was posted on November 1st 2023 and its data has been amended as recently as December 4th 2023. Forty individuals between one centre are sought after for this study.

Phase < 1

Recruiting

Research Sponsored by Anna Stanhewicz, PhD

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

18 years or older

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 12 weeks

Awards & highlights

Study Summary

This trial is examining if low dose aspirin therapy after pregnancy can help prevent cardiovascular disease in women who had preeclampsia during pregnancy.

Who is the study for?

This trial is for women aged 18 or older who had preeclampsia within the last 5 years. It's not suitable for those currently on daily aspirin, with skin diseases, using tobacco/nicotine, having liver/kidney disease, taking cholesterol or blood pressure meds, with a history of hypertension before pregnancy, gestational diabetes, currently pregnant, underweight (BMI <18.5), allergic to latex or study drugs, or with bleeding disorders and certain stomach issues.Check my eligibility

What is being tested?

The study investigates if low dose aspirin therapy after pregnancy can prevent cardiovascular disease in women who've had preeclampsia by treating lasting blood vessel damage. Participants will either receive daily aspirin treatment or a placebo to compare effectiveness.See study design

What are the potential side effects?

Aspirin may cause side effects like gastrointestinal upset including stomach pain and heartburn; increased risk of bleeding; allergic reactions; and possibly bruising more easily.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

magnitude of brachial artery endothelial function

magnitude of microvascular endothelial function

magnitude of microvascular endothelin-1 mediated constriction

Secondary outcome measures

magnitude of microvascular nitric oxide-dependent dilation

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: aspirinExperimental Treatment1 Intervention

162mg aspirin taken once daily at bedtime for 12 weeks

Group II: placeboPlacebo Group1 Intervention

placebo pill taken once daily at bedtime for 12 weeks

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Aspirin

2014

Completed Phase 4

~55580

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Anna Stanhewicz, PhDLead Sponsor

9 Previous Clinical Trials

340 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does the eligibility criterion for this experiment encompass citizens above 25 years of age?

"This study is recruiting adults aged 18-50."

Answered by AI

Who is eligible to join this medical experiment?

"The eligible age range for this clinical trial is between 18 and 50. As a requirement, applicants must have preeclampsia prophylaxis. 40 individuals are needed to complete the study's cohort."

Answered by AI

What is the maximal number of participants enrolled in this clinical investigation?

"Affirmative. Clinicaltrials.gov has information indicating that this clinical trial, which was inaugurated on the 1st of November 2023, is currently enrolling participants. 40 individuals from a single medical facility are necessary for successful recruitment."

Answered by AI

Does enrollment for this clinical trial remain open?

"Affirmative. The most recent version of the information on clinicaltrials.gov shows that this trial is actively seeking out participants; it was posted on November 1st 2023 and its data has been amended as recently as December 4th 2023. Forty individuals between one centre are sought after for this study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Daily Aspirin Treatment After Preeclampsia

Anna Stanhewicz, PhD 2023. "Daily Aspirin Treatment After Preeclampsia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06168461.

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