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2D Antiscatter Grids on CBCT for Cancer Imaging Quality

N/A

Recruiting

Led By Cem E Altunbas

Research Sponsored by University of Colorado, Denver

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Participants who will be treated with CBCT-guided photon therapy for upper abdomen, prostate, head and neck cancers, or with CBCT-guided proton therapy for prostate cancer

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 years

Awards & highlights

Study Summary

This trial assesses if a 2D antiscatter technology improves CBCT image quality for better tissue visualization. #medtech

Who is the study for?

This trial is for adults aged 18-100 who are undergoing CBCT-guided therapy for certain cancers in the upper abdomen, prostate, or head and neck. They must be able to lie still during imaging and treatment, sign a consent form, follow study procedures, and not have metallic implants in the scan area (some dental materials may be okay). Pregnant individuals cannot participate.Check my eligibility

What is being tested?

The study is testing whether a new technology called a 2D antiscatter grid can improve image quality in CBCT scans used for treating specific cancers. Participants' tissue visualization will be assessed blindly by observers to see if there's an improvement.See study design

What are the potential side effects?

Since this trial focuses on imaging quality with no mention of drugs or invasive procedures, side effects are likely minimal. However, participants may experience discomfort from lying still during longer scanning times.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I will be treated with special imaging-guided therapy for cancer in my upper abdomen, prostate, or head and neck.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in tissue visualization in CBCT images

Secondary outcome measures

Comparison of tissue delineation in CBCT images by auto-segmentation software.

Other outcome measures

Concordance Correlation Coefficients

Trial Design

1Treatment groups

Experimental Treatment

Group I: Participants ScannedExperimental Treatment1 Intervention

All participants will be scanned with a CBCT system equipped with 2D antiscatter grid technology, referred to as research CBCT. Each participant will also be scanned with a standard clinical CBCT as part of their standard clinical care, which will serve as the baseline, or control.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of Colorado, DenverLead Sponsor

1,738 Previous Clinical Trials

2,149,484 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,665 Previous Clinical Trials

40,925,812 Total Patients Enrolled

Cem E AltunbasPrincipal InvestigatorUniversity of Colorado, Denver

Media Library

Research CBCT Clinical Trial Eligibility Overview. Trial Name: NCT04565457 — N/A

Head and Neck Cancers Research Study Groups: Participants Scanned

Head and Neck Cancers Clinical Trial 2023: Research CBCT Highlights & Side Effects. Trial Name: NCT04565457 — N/A

Research CBCT 2023 Treatment Timeline for Medical Study. Trial Name: NCT04565457 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this trial open to participants aged eighty and over?

"The minimum age of admission for this medical trial is 18 and the upper cap is 100."

Answered by AI

Is it feasible to become a participant in this research project?

"Eligibility criteria for this trial stipulate that abdominal cancer patients aged between 18 and 100 may apply. Presently, the team is looking to recruit 40 participants in total."

Answered by AI

Is participation in this research study currently available?

"Per the clinicaltrials.gov website, this medical research is presently seeking participants for their trial that was first posted on February 13th 2023 and last updated in April 11th of the same year."

Answered by AI

What is the sample size for this research project?

"Affirmative. Clinicaltrials.gov attests that this medical study, which was initially published on February 13th 2023, is actively recruiting patients. Approximately 40 individuals need to be enrolled from one location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality

2023. "A Pilot Study Evaluating the Effect of 2D Antiscatter Grids on CBCT Image Quality". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04565457.