Treatment Arm for Retinal Telangiectasia

Phase-Based Progress Estimates
Duke Eye Center, Durham, NCRetinal Telangiectasia+8 MoreDextenza 0.4Mg Ophthalmic Insert - Drug
3 - 17
All Sexes
What conditions do you have?

Study Summary

This trial investigates the safety and effectiveness of a medical insert in children who have had eye surgery or laser treatment while under anesthesia.

Eligible Conditions
  • Retinal Telangiectasia
  • Vitreoretinopathy
  • Exudative Retinopathy
  • Lattice Degeneration
  • Retinal Hole
  • Sickle Cell Disease
  • Rhegmatogenous Retinal Detachment
  • Retinal Detachment Exudative
  • Retinal Detachment

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 12 Secondary · Reporting Duration: up to Day 45 post-op

Day 45
Caregivers Treatment Adherence
Cell Count
Incidence of adverse events
Mean change in BCVA
Mean change in Best Corrected Visual Assessment (BCVA)
Ratio of Intraocular pressure increase with insert
Severity of Adverse Events
The number of drops needed in these patients

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Control Arm
1 of 2
Treatment Arm
1 of 2

Active Control

Experimental Treatment

30 Total Participants · 2 Treatment Groups

Primary Treatment: Treatment Arm · No Placebo Group · Phase < 1

Treatment Arm
Experimental Group · 1 Intervention: Dextenza 0.4Mg Ophthalmic Insert · Intervention Types: Drug
Control Arm
ActiveComparator Group · 1 Intervention: Pred Forte · Intervention Types: Drug
First Studied
Drug Approval Stage
How many patients have taken this drug
Dextenza 0.4Mg Ophthalmic Insert
Completed Phase 4

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: up to day 45 post-op

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,207 Previous Clinical Trials
3,220,759 Total Patients Enrolled
Lejla Vajzovic, MDPrincipal InvestigatorDuke Eye Center
1 Previous Clinical Trials
88 Total Patients Enrolled

Eligibility Criteria

Age 3 - 17 · All Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Children who are having regular eye surgery or laser treatment while under anesthesia for different eye problems. Some examples of these conditions and procedures are:

Frequently Asked Questions

Are they accepting participants below the age of fifty-five for this trial?

"For this research, our team is recruiting participants between the ages of three and seventeen." - Anonymous Online Contributor

Unverified Answer

Who is eligible to take part in this experiment?

"This medical study seeks 30 participants aged between 3 and 17 that suffer from retinal telangiectasis. To be eligible, applicants must demonstrate Familial Exudative Vitreoretinopathy, Exudative Retinopathy, Lattice degeneration, Retinal holes, Sickler's syndrome, Retinal detachment (rhegmatogenous or exudative/tractional), Procedures or Coats' Disease." - Anonymous Online Contributor

Unverified Answer

Are there vacancies for participants in this test?

"According to information facilitated by, this research study is not currently enrolling participants. This trial was initially posted on November 1st 2022 and last edited on the 10th of that same month. Despite this, there are 41 other studies recruiting patients at the moment." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.