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Ascorbic Acid for Skin Cancer

Phase < 1
Recruiting
Research Sponsored by Center for Biomedical Research, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Presence of biopsy proven squamous cell cancer of the skin
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

Study Summary

This trial tested 2 treatments for skin cancer: a 30% ascorbic acid solution and 5% imiquimod cream. After 8 weeks, results showed which was more effective.

Who is the study for?
This trial is for adults with biopsy-proven squamous cell skin cancer. It's not suitable for those who've had other cancers, have diabetes, or are immunocompromised.Check my eligibility
What is being tested?
The study tests a topical solution of 30% ascorbic acid in DMSO against a standard treatment (5% imiquimod cream) to see which is better at clearing up squamous cell carcinomas of the skin over an 8-week period.See study design
What are the potential side effects?
Potential side effects may include skin irritation, redness, and discomfort where the ascorbic acid solution or imiquimod cream is applied.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have been diagnosed with squamous cell skin cancer through a biopsy.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Lesion Resolution

Side effects data

From 2016 Phase 1 & 2 trial • 5 Patients • NCT01754987
40%
Elevated Creatinine
40%
Low Platelet count
20%
Dehydration
20%
Thrush
20%
Nosebleed
100%
80%
60%
40%
20%
0%
Study treatment Arm
Ascorbic Acid + Sorafenib
Sorafenib Alone

Trial Design

1Treatment groups
Experimental Treatment
Group I: 30% Ascorbic Acid in DMSOExperimental Treatment1 Intervention
Topical application twice daily of 300ul 30% (w/v) solution of ascorbic acid in DMSO

Find a Location

Who is running the clinical trial?

Center for Biomedical Research, Inc.Lead Sponsor
2 Previous Clinical Trials
67 Total Patients Enrolled

Media Library

Topical Ascorbic Acid (Other) Clinical Trial Eligibility Overview. Trial Name: NCT05932511 — Phase < 1
Non-melanoma Skin Cancer Research Study Groups: 30% Ascorbic Acid in DMSO
Non-melanoma Skin Cancer Clinical Trial 2023: Topical Ascorbic Acid Highlights & Side Effects. Trial Name: NCT05932511 — Phase < 1
Topical Ascorbic Acid (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05932511 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment for this trial ongoing at present?

"The clinical trial is still recruiting, according to the information available on clinicialtrials.gov. This study was made public on August 1st 2023 and has since had a few updates in July 2nd of the same year."

Answered by AI

Does the trial enrollment include individuals aged 75 and older?

"This clinical trial specifies that all participants must be 18 years of age or older, and not exceed 85 years old."

Answered by AI

Am I eligible to enroll in this investigation?

"To be eligible for this research trial, prospective participants should possess squamous cell cancer and are aged between 18 - 85 years old. This study is only recruiting 15 volunteers."

Answered by AI

To what extent is the current research involving volunteers?

"Affirmative. According to clinicaltrials.gov, this experiment commenced on August 1st 2023 and is actively welcoming participants at the moment. 15 individuals need to be consented across a solitary site before enrollment can conclude."

Answered by AI
~7 spots leftby Dec 2024