15 Participants Needed

Ascorbic Acid for Skin Cancer

Age: 18+
Sex: Any
Trial Phase: Phase < 1
Sponsor: Center for Biomedical Research, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

This trial tests a vitamin C solution and an approved cream for treating a specific type of skin cancer in adults. The vitamin C solution aims to kill cancer cells and reduce inflammation, while the cream boosts the immune system to fight cancer. Vitamin C has been studied for its various health benefits.

Eligibility Criteria

This trial is for adults with biopsy-proven squamous cell skin cancer. It's not suitable for those who've had other cancers, have diabetes, or are immunocompromised.

Inclusion Criteria

I have been diagnosed with squamous cell skin cancer through a biopsy.

Exclusion Criteria

I have had cancer before.
I have diabetes.
My immune system is weak.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive either 30% ascorbic acid in DMSO or 5% imiquimod cream applied topically for 8 weeks

8 weeks
Initial visit, 4-week visit, 8-week visit

Follow-up

Participants are monitored for safety and effectiveness after treatment, including a final biopsy

6 weeks
1 visit (in-person) for final biopsy

Treatment Details

Interventions

  • Topical Ascorbic Acid
Trial Overview The study tests a topical solution of 30% ascorbic acid in DMSO against a standard treatment (5% imiquimod cream) to see which is better at clearing up squamous cell carcinomas of the skin over an 8-week period.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: 30% Ascorbic Acid in DMSOExperimental Treatment1 Intervention
Topical application twice daily of 300ul 30% (w/v) solution of ascorbic acid in DMSO

Find a Clinic Near You

Who Is Running the Clinical Trial?

Center for Biomedical Research, Inc.

Lead Sponsor

Trials
3
Recruited
80+
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