Dr. Vitaly Margulis
Claim this profileUniversity of Texas Southwestern Medical Center
Studies Kidney Cancer
Studies Bladder Cancer
7 reported clinical trials
20 drugs studied
Area of expertise
1Kidney Cancer
Stage I
Stage II
Stage III
2Bladder Cancer
cN+
radiologic complete response
Stage II
Affiliated Hospitals
Clinical Trials Vitaly Margulis is currently running
Metabolic Tracers
for Kidney Cancer
The purpose of this study is to understand the metabolism of cancers involving the kidney, including renal cell carcinomas and urothelial cell carcinomas, and how kidney cancers use different types of fuel to support tumor growth. This study uses specially labeled nutrient tracers of compounds normally found circulating in the blood. The nutrients (glucose, fructose, glutamine, acetate, and lactate) are also found in common foods. A nutrient tracer will be given to the participants through an intravenous (IV) catheter during surgery or biopsy, and blood will be collected every 30 minutes during the infusion to monitor safety parameters and the nutrient tracers. The investigators will collect a tissue sample after the completion of surgery. Participants not having an infusion will have their tissue collected after surgery or biopsy. Participation in this study will not change patient care. All patients will receive standard of care treatment as determined by their doctors.
Recruiting1 award N/A5 criteria
Gemcitabine vs Water Irrigation
for Urothelial Cancer
There is a high rate of intravesical (bladder) recurrence following extirpative surgery for upper tract urothelial carcinoma. There is no single established standard of care for prevention of intravesical recurrence; however, one protocol in common use involves the use of intravesical gemcitabine instilled into the bladder during surgery and prior to entry into the bladder. There are barriers to the use of gemcitabine, especially at lower volume centers. Some evidence suggests that intravesical irrigation with sterile water has equivalent efficacy to intravesical chemotherapy in prevention of recurrent bladder cancer following transurethral resection of bladder tumors (TURBT). This study is intended to compare recurrence rates using intravesical gemcitabine (as a pseudo-standard of care) and continuous bladder irrigation with sterile water.
Recruiting2 awards Phase 35 criteria
More about Vitaly Margulis
Clinical Trial Related6 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 6 Active Clinical TrialsTreatments Vitaly Margulis has experience with
- Padeliporfin VTP
- Lenvatinib
- Pembrolizumab
- 13C-Glucose
- 13C-Lactate
- 13C-Glutamine
Breakdown of trials Vitaly Margulis has run
Kidney Cancer
Bladder Cancer
Urothelial Carcinoma
Renal Cell Carcinoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Vitaly Margulis specialize in?
Vitaly Margulis focuses on Kidney Cancer and Bladder Cancer. In particular, much of their work with Kidney Cancer has involved Stage I patients, or patients who are Stage II.
Is Vitaly Margulis currently recruiting for clinical trials?
Yes, Vitaly Margulis is currently recruiting for 6 clinical trials in Dallas Texas. If you're interested in participating, you should apply.
Are there any treatments that Vitaly Margulis has studied deeply?
Yes, Vitaly Margulis has studied treatments such as Padeliporfin VTP, Lenvatinib, Pembrolizumab.
What is the best way to schedule an appointment with Vitaly Margulis?
Apply for one of the trials that Vitaly Margulis is conducting.
What is the office address of Vitaly Margulis?
The office of Vitaly Margulis is located at: University of Texas Southwestern Medical Center, Dallas, Texas 75390 United States. This is the address for their practice at the University of Texas Southwestern Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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