dir VCU School of Medicine

Dr. Victor Y. Yazbeck

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Virginia Commonwealth University/Massey Cancer Center

Studies Lymphoma
Studies Mixed-Cell Lymphoma
9 reported clinical trials
21 drugs studied

Area of expertise

1Lymphoma
Victor Y. Yazbeck has run 6 trials for Lymphoma. Some of their research focus areas include:
CD30 negative
HTLV-1 positive
Stage I
2Mixed-Cell Lymphoma
Victor Y. Yazbeck has run 4 trials for Mixed-Cell Lymphoma. Some of their research focus areas include:
EZH2 negative
EZH2 positive

Affiliated Hospitals

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Virginia Commonwealth University/Massey Cancer Center
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Virginia Commonwealth University Medical Center

Clinical Trials Victor Y. Yazbeck is currently running

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Social and Genetic Factors

for Lymphoma Survivors

This study examines the impact of social and genetic factors on outcomes in adolescent and young adult (AYA) cancer survivors of Hodgkin or non-Hodgkin lymphoma. Compared to both older adult and childhood cancer patients, AYAs with cancer experience different diagnoses and specific biological, clinical, psychological and social factors that affect their risks for post-treatment morbidity and premature death. Collecting samples of blood samples and health and treatment information from cancer survivors of Hodgkin or non-Hodgkin lymphoma may help doctors identify conditions that increase the likelihood of AYAs getting sick and dying after treatment of cancer and better understand how to address the needs of adolescent and young adult cancer survivors.
Recruiting1 award N/A10 criteria
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Tazemetostat + Belinostat

for Lymphoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with tazemetostat and belinostat in treating patients with lymphoma that has come back after a period of improvement (relapsed) or that does not respond to treatment (refractory). Tazemetostat is in a class of medications called EZH2 inhibitors. The EZH2 gene provides instructions for making a type of enzyme called histone methyltransferase which is involved in gene expression and cell division. Blocking EZH2 may help keep cancer cells from growing. Belinostat is in a class of medications called histone deacetylase inhibitors. Histone deacetylases are enzymes needed for cell division. Belinostat may kill cancer cells by blocking histone deacetylase. It may also prevent the growth of new blood vessels that tumors need to grow and may help make cancer cells easier to kill with other anticancer drugs. There is some evidence in animals and in living human cells that combination therapy with tazemetostat and belinostat can shrink or stabilize cancer, but it is not known whether this will happen in people. This trial may help doctors learn more about treatment of patients with relapsed or refractory lymphoma.
Recruiting1 award Phase 1

More about Victor Y. Yazbeck

Clinical Trial Related13 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Victor Y. Yazbeck has experience with
  • Brentuximab Vedotin
  • Rituximab
  • Venetoclax
  • Cyclophosphamide
  • Doxorubicin
  • Prednisone

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