Dr. Thomas J. Saphner
Claim this profileAurora Saint Luke's Medical Center
Expert in Parotid Gland Cancer
Studies Breast Cancer
30 reported clinical trials
68 drugs studied
Area of expertise
1Parotid Gland Cancer
Global LeaderHER2 positive
Stage III
ER positive
2Breast Cancer
HER2 positive
ER positive
ER negative
Affiliated Hospitals
Clinical Trials Thomas J. Saphner is currently running
Chemotherapy + Hormone Therapy
for Breast Cancer
This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.
Recruiting2 awards Phase 319 criteria
Lomustine + Standard Therapy
for Glioblastoma
This phase III trial compares the effect of adding lomustine to standard chemotherapy with temozolomide and radiation therapy versus temozolomide and radiation therapy alone in shrinking or stabilizing newly diagnosed MGMT methylated glioblastoma. MGMT methylated tumors are more likely to respond to temozolomide chemotherapy. Temozolomide is in a class of medications called alkylating agents. It works by damaging the cell's DNA and may kill tumor cells and slow down or stop tumor growth. Lomustine is a chemotherapy drug and in a class of medications called alkylating agents. It damages the cell's DNA and may kill tumor cells. Radiation therapy uses high energy x-ray photons to kill tumor cells and shrink tumors. Adding lomustine to standard chemotherapy with temozolomide and radiation therapy may shrink or stabilize glioblastoma.
Recruiting2 awards Phase 34 criteria
More about Thomas J. Saphner
Clinical Trial Related1 year of experience running clinical trials · Led 30 trials as a Principal Investigator · 21 Active Clinical TrialsTreatments Thomas J. Saphner has experience with
- Biospecimen Collection
- Pembrolizumab
- Questionnaire Administration
- Lenalidomide
- Therapeutic Conventional Surgery
- Binimetinib
Breakdown of trials Thomas J. Saphner has run
Parotid Gland Cancer
Breast Cancer
Cancer
Lung Cancer
Cystic Tumor
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