Stanton C. Goldman, M.D. | Texas Oncology

Dr. Stanton C. Goldman

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Medical City Dallas Hospital

Expert in Cancer
Expert in Neuroblastoma
56 reported clinical trials
104 drugs studied

About Stanton C. Goldman

Education:

  • Earned an MD from Boston University School of Medicine in 1990.
  • Completed Residency in General Pediatrics at Children's National Medical Center, Washington, D.C. (1990-1993).
  • Undertook a Fellowship in Pediatric Hematology/Oncology at Johns Hopkins University Medical Center, Baltimore (1993-1996).

Experience:

  • Board certified in Hematology-Oncology by the American Board of Pediatrics.
  • Over 33 years of experience in Pediatrics, with affiliations to Medical City Dallas and Medical City Plano.
  • Serves as the Principal Investigator for the Children's Oncology Group at Medical City Dallas and Chief Medical Officer for Medical City Children's Hospital.
  • Authored over 30 articles and several book chapters on tumor lysis syndrome and pediatric mature B non-Hodgkin lymphoma.

Area of expertise

1Cancer
Global Leader
Stanton C. Goldman has run 20 trials for Cancer. Some of their research focus areas include:
Stage I
Stage IV
Stage II
2Neuroblastoma
Global Leader
Stanton C. Goldman has run 18 trials for Neuroblastoma. Some of their research focus areas include:
MYC positive
Stage IV
MYC negative

Affiliated Hospitals

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Medical City Dallas Hospital

Clinical Trials Stanton C. Goldman is currently running

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Inotuzumab Ozogamicin

for Acute Lymphoblastic Leukemia

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting2 awards Phase 3
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Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.
Recruiting1 award Phase 1 & 21 criteria

More about Stanton C. Goldman

Clinical Trial Related8 years of experience running clinical trials · Led 56 trials as a Principal Investigator · 19 Active Clinical Trials
Treatments Stanton C. Goldman has experience with
  • Cyclophosphamide
  • Radiation Therapy
  • Etoposide
  • Doxorubicin Hydrochloride
  • Vincristine Sulfate
  • Laboratory Biomarker Analysis

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