Seth M Pollack: Faculty Profiles ...

Dr. Seth M. Pollack

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Northwestern University

Studies Soft Tissue Sarcoma
Studies Cancer
18 reported clinical trials
28 drugs studied

Area of expertise

1

Soft Tissue Sarcoma

Seth M. Pollack has run 7 trials for Soft Tissue Sarcoma. Some of their research focus areas include:

Stage IV
Stage III
FGFR positive
2

Cancer

Seth M. Pollack has run 6 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
FGFR positive

Affiliated Hospitals

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Northwestern University

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Northwestern Medicine Cancer Center Kishwaukee

Clinical Trials Seth M. Pollack is currently running

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ADI-PEG 20 + Chemotherapy

for Leiomyosarcoma

To compare the efficacy and safety in subjects with advanced or metastatic LMS previously treated with an anthracycline.

Recruiting

1 award

Phase 3

10 criteria

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Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

More about Seth M. Pollack

Clinical Trial Related

2 years of experience running clinical trials · Led 18 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Seth M. Pollack has experience with

  • Cabozantinib
  • Placebo
  • Doxorubicin
  • Temozolomide
  • Nivolumab
  • Dacarbazine

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