Dr. Sarah Leary, MD
Claim this profileSeattle Children's Hospital
Expert in Brain Tumor
Expert in Brain Cancer
78 reported clinical trials
139 drugs studied
About Sarah Leary, MD
Education:
- Earned an MD (Doctor of Medicine).
- Holds an MS (Master of Science).
Experience:
- Since August 2009, serves as Attending Physician and Medical Director of the Pediatric Brain Tumor Program at Seattle Children's Hospital.
- Professor in the Department of Pediatrics at the University of Washington School of Medicine.
- Medical Director of Clinical Research at the Ben Towne Center for Childhood Cancer Research.
- Actively involved in national and international pediatric brain tumor research and data sharing initiatives.
- Recognized as Seattle's Top Doctor in 2022 by Seattle Magazine.
Area of expertise
1Brain Tumor
Global LeaderNTRK positive
H3.3K27M positive
Stage IV
2Brain Cancer
Global LeaderStage IV
Stage I
Stage II
Affiliated Hospitals
Clinical Trials Sarah Leary, MD is currently running
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting2 awards Phase 3
Inotuzumab Ozogamicin
for Acute Lymphoblastic Leukemia
This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting2 awards Phase 3
More about Sarah Leary, MD
Clinical Trial Related8 years of experience running clinical trials · Led 78 trials as a Principal Investigator · 30 Active Clinical TrialsTreatments Sarah Leary, MD has experience with
- Cyclophosphamide
- Radiation Therapy
- Nivolumab
- Etoposide
- Cisplatin
- Doxorubicin Hydrochloride
Breakdown of trials Sarah Leary, MD has run
Brain Tumor
Brain Cancer
Cancer
Solid Tumors
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Sarah Leary, MD specialize in?
Sarah Leary, MD focuses on Brain Tumor and Brain Cancer. In particular, much of their work with Brain Tumor has involved NTRK positive patients, or patients who are H3.3K27M positive.
Is Sarah Leary, MD currently recruiting for clinical trials?
Yes, Sarah Leary, MD is currently recruiting for 30 clinical trials in Seattle Washington. If you're interested in participating, you should apply.
Are there any treatments that Sarah Leary, MD has studied deeply?
Yes, Sarah Leary, MD has studied treatments such as Cyclophosphamide, Radiation Therapy, Nivolumab.
What is the best way to schedule an appointment with Sarah Leary, MD?
Apply for one of the trials that Sarah Leary, MD is conducting.
What is the office address of Sarah Leary, MD?
The office of Sarah Leary, MD is located at: Seattle Children's Hospital, Seattle, Washington 98105 United States. This is the address for their practice at the Seattle Children's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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