Dr. Robert Naftel, MD

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Monroe Carell Jr. Children's Hospital at Vanderbilt

Studies Hydrocephalus
2 reported clinical trials
2 drugs studied

Affiliated Hospitals

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Monroe Carell Jr. Children's Hospital At Vanderbilt

Clinical Trials Robert Naftel, MD is currently running

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Endoscopic Treatment vs. Shunt Surgery

for Hydrocephalus

Hydrocephalus is a potentially debilitating neurological condition that primarily affects babies under a year of age and has traditionally been treated by inserting a shunt between the brain and the abdomen. A newer endoscopic procedure offers hope of shunt- free treatment that may reduce complications over a child's life, but it is not clear if the endoscopic procedure results in similar intellectual outcome as shunt. Therefore, the investigators propose a randomized trial to compare intellectual outcome and brain structural integrity between these two treatments, to help families make the best treatment decision for their baby.

Recruiting

2 awards

Phase 3

4 criteria

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Data Collection

for Pediatric Hydrocephalus

The Hydrocephalus Clinical Research Network (HCRN) has been established by philanthropic funding to conduct multi-institutional research (clinical trials and observational studies) on pediatric hydrocephalus. In addition to philanthropic funding, the HCRN has also received an NIH NINDS Challenge Grant to support the network infrastructure which allows for the conduct of this and other network studies. The HCRN consists of multiple Clinical Centers and the Data Coordinating Center (DCC). The HCRN Core Data Project will obtain data about all neurosurgical hydrocephalus events from the network Clinical Centers, and create a database to be used by HCRN investigators. The ongoing maintenance of the Core Data Project serves two main purposes: 1) it will help investigators understand the variability, progression, and current treatment practices for hydrocephalus in children, with an ultimate goal of better guiding and assessing therapeutic intervention and providing recommendations on patient care and, 2) it will provide pilot and descriptive data necessary for hypothesis generation and study design (i.e. preliminary power analyses, recruitment projections) for studies under development by the HCRN. This multi-institutional database will be maintained throughout the lifetime of the HCRN, and may be useful for tracking trends in pediatric hydrocephalus over time. The Core Data Project will be an invaluable resource to the HCRN and will help stimulate new research protocols, identify potential need for future expansion of the network to incorporate additional patient populations, and provide a descriptive understanding of children with hydrocephalus cared for within the network.

Recruiting

1 award

N/A

10 criteria

More about Robert Naftel, MD

Clinical Trial Related

5 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Robert Naftel, MD has experience with

  • Endoscopic Third Ventriculostomy With Choroid Plexus Cauterization (ETV+CPC)
  • Ventriculoperitoneal Shunt

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