Dr. Richard L. Jennelle, MD | Los ...

Dr. Richard L. Jennelle

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USC / Norris Comprehensive Cancer Center

Studies Prostate Adenocarcinoma
Studies Prostate Cancer
5 reported clinical trials
20 drugs studied

Affiliated Hospitals

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USC / Norris Comprehensive Cancer Center
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Los Angeles County-USC Medical Center

Clinical Trials Richard L. Jennelle is currently running

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Relugolix + Radiation

for Advanced-Stage Prostate Cancer

This phase II trial compares the usual treatment of radiation therapy alone to using the study drug, relugolix, plus the usual radiation therapy in patients with castration-sensitive prostate cancer that has spread to limited other parts of the body (oligometastatic). Relugolix is in a class of medications called gonadotropin-releasing hormone (GnRH) receptor antagonists. It works by decreasing the amount of testosterone (a male hormone) produced by the body. It may stop the growth of cancer cells that need testosterone to grow. Radiation therapy uses high-energy x rays or protons to kill tumor cells. The addition of relugolix to the radiation may reduce the chance of oligometastatic prostate cancer spreading further.
Recruiting0 awards Phase 2
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Apalutamide + Hormone and Radiation Therapies

for Prostate Cancer

This phase III trial studies whether adding apalutamide to the usual treatment improves outcome in patients with lymph node positive prostate cancer after surgery. Radiation therapy uses high energy x-ray to kill tumor cells and shrink tumors. Androgens, or male sex hormones, can cause the growth of prostate cancer cells. Drugs, such as apalutamide, may help stop or reduce the growth of prostate cancer cell growth by blocking the attachment of androgen to its receptors on cancer cells, a mechanism similar to stopping the entrance of a key into its lock. Adding apalutamide to the usual hormone therapy and radiation therapy after surgery may stabilize prostate cancer and prevent it from spreading and extend time without disease spreading compared to the usual approach.
Recruiting2 awards Phase 3

More about Richard L. Jennelle

Clinical Trial Related9 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Richard L. Jennelle has experience with
  • Radiation Therapy
  • Relugolix
  • Hippocampal Avoidance
  • Whole-Brain Radiation Therapy
  • Atezolizumab
  • Cisplatin

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