James S. Hu - Keck Medicine of USC

Dr. James Hu, MD

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USC / Norris Comprehensive Cancer Center

Studies Cancer
Studies Soft Tissue Sarcoma
10 reported clinical trials
18 drugs studied

Area of expertise

1Cancer
James Hu, MD has run 6 trials for Cancer. Some of their research focus areas include:
Stage IV
EWSR1/ATF1 positive
EWSR1/CREB1 positive
2Soft Tissue Sarcoma
James Hu, MD has run 6 trials for Soft Tissue Sarcoma. Some of their research focus areas include:
Stage IV
Stage III
EWSR1/ATF1 positive

Affiliated Hospitals

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USC / Norris Comprehensive Cancer Center
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Los Angeles County-USC Medical Center

Clinical Trials James Hu, MD is currently running

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Atezolizumab +/− Selinexor

for Sarcoma

This trial is testing if atezolizumab alone or with selinexor can shrink tumors in patients with a rare type of cancer called alveolar soft part sarcoma. Atezolizumab boosts the immune system to fight cancer, and selinexor stops cancer cells from growing. The goal is to see if these treatments work better than the usual care.
Recruiting1 award Phase 2
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Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.
Recruiting2 awards Phase 310 criteria

More about James Hu, MD

Clinical Trial Related3 years of experience running clinical trials · Led 10 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments James Hu, MD has experience with
  • Atezolizumab
  • Perillyl Alcohol
  • TP-1287
  • INT230-6
  • Bevacizumab
  • Carboplatin

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