Dr. REX MOWAT, MD
Claim this profileToledo Clinic Cancer Centers-Toledo
Expert in Lung Cancer
Expert in Breast Cancer
79 reported clinical trials
151 drugs studied
About REX MOWAT, MD
Education:
- Earned an MD (Doctor of Medicine).
Experience:
- Currently a practicing physician at the Toledo Clinic Cancer Center with a specialization in oncology.
- Collaborates with the Barbara Ann Karmanos Cancer Institute to enhance access to advanced cancer care, clinical trials, and precision medicine in Northwest Ohio.
Area of expertise
1Lung Cancer
Global LeaderStage IV
Stage III
Stage II
2Breast Cancer
Global LeaderStage IV
HER2 negative
PR negative
Affiliated Hospitals
Clinical Trials REX MOWAT, MD is currently running
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
More about REX MOWAT, MD
Clinical Trial Related2 years of experience running clinical trials · Led 79 trials as a Principal Investigator · 24 Active Clinical TrialsTreatments REX MOWAT, MD has experience with
- Pembrolizumab
- Nivolumab
- Carboplatin
- Fluorouracil
- Paclitaxel
- Ipilimumab
Breakdown of trials REX MOWAT, MD has run
Lung Cancer
Breast Cancer
Cancer
Pancreatic Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does REX MOWAT, MD specialize in?
REX MOWAT, MD focuses on Lung Cancer and Breast Cancer. In particular, much of their work with Lung Cancer has involved Stage IV patients, or patients who are Stage III.
Is REX MOWAT, MD currently recruiting for clinical trials?
Yes, REX MOWAT, MD is currently recruiting for 24 clinical trials in Toledo Ohio. If you're interested in participating, you should apply.
Are there any treatments that REX MOWAT, MD has studied deeply?
Yes, REX MOWAT, MD has studied treatments such as Pembrolizumab, Nivolumab, Carboplatin.
What is the best way to schedule an appointment with REX MOWAT, MD?
Apply for one of the trials that REX MOWAT, MD is conducting.
What is the office address of REX MOWAT, MD?
The office of REX MOWAT, MD is located at: Toledo Clinic Cancer Centers-Toledo, Toledo, Ohio 43623 United States. This is the address for their practice at the Toledo Clinic Cancer Centers-Toledo.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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