Dr. Polina Khrizman
Claim this profileCooper Hospital University Medical Center
Studies Non-Small Cell Lung Cancer
Studies Lung Cancer
6 reported clinical trials
12 drugs studied
Area of expertise
1Non-Small Cell Lung Cancer
Stage II
Stage I
Stage III
2Lung Cancer
Stage II
Stage I
Stage III
Affiliated Hospitals
Clinical Trials Polina Khrizman is currently running
Crizotinib
for Non-Small Cell Lung Cancer
This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by blocking the ALK protein from working. Crizotinib may be an effective treatment for patients with non-small cell lung cancer and an ALK fusion mutation.
Recruiting2 awards Phase 328 criteria
Immunotherapy + Chemotherapy
for Non-Small Cell Lung Cancer
This phase III ALCHEMIST trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.
Recruiting2 awards Phase 327 criteria
More about Polina Khrizman
Clinical Trial Related10 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Polina Khrizman has experience with
- Pembrolizumab
- Biospecimen Collection
- Crizotinib
- Carboplatin
- Gemcitabine Hydrochloride
- Paclitaxel
Breakdown of trials Polina Khrizman has run
Non-Small Cell Lung Cancer
Lung Cancer
Thyroid Cancer
Anaplastic Large Cell Lymphoma
ALK Gene Rearrangement
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