Paul E. Oberstein, MD | NYU Langone Health

Dr. Paul Oberstein, MD

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NYU Langone Health

Expert in Pancreatic Cancer
Studies Colorectal Cancer
21 reported clinical trials
49 drugs studied

About Paul Oberstein, MD

Education:

  • Received an MD (Doctor of Medicine) from New York University School of Medicine in 2009.

Experience:

  • Serves as Assistant Professor of Medicine in the Division of Hematology and Medical Oncology at Perlmutter Cancer Center, NYU Langone Health.
  • Holds the position of Clinical Director of the Lymphoma Program at Perlmutter Cancer Center, NYU Langone Health.

Area of expertise

1Pancreatic Cancer
Global Leader
Paul Oberstein, MD has run 13 trials for Pancreatic Cancer. Some of their research focus areas include:
Stage IV
Stage III
BRCA1 positive
2Colorectal Cancer
Paul Oberstein, MD has run 6 trials for Colorectal Cancer. Some of their research focus areas include:
Stage IV
MSS positive
MMR positive

Affiliated Hospitals

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NYU Langone Health
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Laura And Isaac Perlmutter Cancer Center At NYU Langone

Clinical Trials Paul Oberstein, MD is currently running

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Olaparib

for Pancreatic Cancer

This phase II trial investigates how well the addition of olaparib following completion of surgery and chemotherapy works in treating patients with pancreatic cancer that has been surgically removed (resected) and has a pathogenic mutation in BRCA1, BRCA2, or PALB2. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy.
Recruiting0 awards Phase 232 criteria
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Combination Therapy

for Pancreatic Cancer

The goal of this Single Arm Phase Ib clinical trial is to test standard of care chemotherapy and anti PD1 and IL1b to evaluate the safety and preliminary toxicity of this quadruplet regimen prior to resection in patients with pancreatic cancer. The main objectives it aims to answer are to: * Determine the recommended Phase II dose regimen of canakinumab and tislelizumab in combination with gemcitabine and nab-paclitaxel in patients with localized pancreatic ductal adenocarcinoma. * Estimate the proportion of patients who proceed to surgical resection. * Determine the safety and tolerability of canakimumab in combination with tislelizumab, nab-paclitaxel and gemcitabine * Assess the preliminary clinical anti-tumor activity of canakimumab in combination with tislelizumab, nab-paclitaxel and gemcitabine * Assess whether therapy has any impact on surgical options Participants will have labs drawn, CT scans, and a treatment administered consisting of: * Gemcitabine * Nab-paclitaxel * Canakinumab * Tislelizumab
Recruiting1 award Phase 110 criteria

More about Paul Oberstein, MD

Clinical Trial Related4 years of experience running clinical trials · Led 21 trials as a Principal Investigator · 5 Active Clinical Trials
Treatments Paul Oberstein, MD has experience with
  • Gemcitabine
  • Nab-paclitaxel
  • Pembrolizumab
  • Ipilimumab
  • Canakinumab
  • Nivolumab

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