Sam Parnia, MD, PhD | NYU Langone Health

Dr. Sam Parnia, MD, PhD

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NYU Langone Health

Studies Cardiac Arrest
Studies Heart Attack
5 reported clinical trials
10 drugs studied

Affiliated Hospitals

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NYU Langone Health

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New York University Langone Medical Center

Clinical Trials Sam Parnia, MD, PhD is currently running

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Magnesium

for Cardiac Arrest

The purpose of this pilot interventional study is to collect preliminary data on administering magnesium sulfate as a neuroprotective medication in patients who achieved Return of Spontaneous Circulation (ROSC) following Cardiac Arrest (CA). The primary aims are to assess the feasibility and safety of administering magnesium and measure serum markers of neuronal injury at prespecified time points in the post-cardiac arrest period. Because this is a pilot study with a limited sample size, the primary objective is to evaluate the precision and stability of the collected measures to inform the design and formal analysis in a larger trial.

Recruiting

0 awards

Phase 1

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Paradoxical Lucidity

for Dementia

Cognitive decline in dementia is considered irreversible, however episodes of paradoxical lucidity (PL) in severe dementia suggest other mechanisms may be in play. Beyond anecdotal reports of transient PL events occurring in patients predominantly in late-stage dementia and typically lasting anywhere from a few minutes to several hours, little is known about PL. The study team proposes to develop and conduct a mixed methods prospective study of PL during end stage advanced dementia, creating a definition and measurement scale for PL in advanced dementia, and identifying the potential electro cortical biomarkers of PL in advanced dementia. This study will be divided in two phases: Phase I and Phase II. During Phase I, the study team will collect sufficient and necessary data through an online survey and focus groups as well as assess the safety and feasibility of using symptom diaries (also known as daily trackers or journals) and real-time video EEG monitoring (vEEG). After preliminary review of the study procedures, the PI will decide whether to move onto the Phase II. The second phase will aim to expand the study population and refine study methods as well as create a definition and measurement scale for PL in advances dementia.

Recruiting

1 award

N/A

5 criteria

More about Sam Parnia, MD, PhD

Clinical Trial Related

1 year of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Sam Parnia, MD, PhD has experience with

  • Magnesium Sulfate
  • Packed Red Blood Cells
  • Non-Physiological Feedback CPR
  • Physiological Feedback CPR
  • Abatacept
  • Cenicriviroc

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