Dr. Paul B. Gilman, MD | Wynnewood, PA ...

Dr. Paul B. Gilman

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Riddle Memorial Hospital

Studies Lung Cancer
Studies Non-Small Cell Lung Cancer
16 reported clinical trials
45 drugs studied

Area of expertise

1Lung Cancer
Paul B. Gilman has run 4 trials for Lung Cancer. Some of their research focus areas include:
Stage IV
Stage III
EGFR positive
2Non-Small Cell Lung Cancer
Paul B. Gilman has run 4 trials for Non-Small Cell Lung Cancer. Some of their research focus areas include:
Stage IV
Stage III
PD-L1 positive

Affiliated Hospitals

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Riddle Memorial Hospital
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Paoli Memorial Hospital

Clinical Trials Paul B. Gilman is currently running

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Osimertinib + Bevacizumab

for Lung Cancer

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
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Chemotherapy + Radiotherapy

for Esophageal and Gastric Cancer

This phase III trial studies how well the addition of radiotherapy to the usual treatment (chemotherapy) works compared to the usual treatment alone in treating patients with esophageal and gastric cancer that has spread to a limited number of other places in the body (oligometastatic disease). Radiotherapy uses high energy x-rays, gamma rays, or protons to kill tumor cells and shrink tumors. Drugs used in usual chemotherapy, such as leucovorin, 5-fluorouracil, oxaliplatin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Adding radiotherapy to the usual chemotherapy may work better compared to the usual chemotherapy alone in treating patients with esophageal and gastric cancer.
Recruiting2 awards Phase 320 criteria

More about Paul B. Gilman

Clinical Trial Related4 years of experience running clinical trials · Led 16 trials as a Principal Investigator · 10 Active Clinical Trials
Treatments Paul B. Gilman has experience with
  • Paclitaxel
  • Binimetinib
  • Olaparib
  • Carboplatin
  • Osimertinib
  • Oxaliplatin

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