Dr. Paul A. DiSilvestro
Claim this profileWomen and Infants Hospital
Studies Ovarian Cancer
Studies Fallopian Tube Cancer
9 reported clinical trials
39 drugs studied
Area of expertise
1Ovarian Cancer
Stage IV
Stage III
BRCA1 positive
2Fallopian Tube Cancer
Stage IV
Stage III
BRCA1 positive
Affiliated Hospitals
Clinical Trials Paul A. DiSilvestro is currently running
Ipatasertib + Chemotherapy
for Cancer
This phase II ComboMATCH treatment trial tests the usual treatment of chemotherapy (paclitaxel) plus ipatasertib in patients with solid tumor cancers that that cannot be removed by surgery (unresectable), has spread to nearby tissue or lymph nodes (locally advanced) or from where it first started (primary site) to other places in the body (metastatic), and has PTEN and AKT genetic changes. Chemotherapy drugs, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Targeted therapy, such as Ipatasertib, may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. The addition of ipatasertib to paclitaxel in solid tumors with PTEN and AKT genetic changes could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression). Researchers hope to learn if paclitaxel plus ipatasertib will shrink this type of cancer or stop its growth.
Recruiting1 award Phase 2
Iohexol-aided Carboplatin Dosing
for Cancer
This trial studies how well iohexol helps doctors calculate the dose of carboplatin for cancer patients. By measuring kidney function more accurately, doctors can improve the effectiveness and safety of carboplatin treatment. Carboplatin is a platinum-based chemotherapy drug used to treat various cancers, known for its improved toxicity profile compared to cisplatin.
Recruiting1 award Phase 17 criteria
More about Paul A. DiSilvestro
Clinical Trial Related2 years of experience running clinical trials · Led 9 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Paul A. DiSilvestro has experience with
- Cisplatin
- Biospecimen Collection
- Olaparib
- Paclitaxel
- Ipatasertib
- Behavioral Dietary Intervention
Breakdown of trials Paul A. DiSilvestro has run
Ovarian Cancer
Fallopian Tube Cancer
Ovarian Adenocarcinoma
Ovarian Carcinoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Paul A. DiSilvestro specialize in?
Paul A. DiSilvestro focuses on Ovarian Cancer and Fallopian Tube Cancer. In particular, much of their work with Ovarian Cancer has involved Stage IV patients, or patients who are Stage III.
Is Paul A. DiSilvestro currently recruiting for clinical trials?
Yes, Paul A. DiSilvestro is currently recruiting for 4 clinical trials in Providence Rhode Island. If you're interested in participating, you should apply.
Are there any treatments that Paul A. DiSilvestro has studied deeply?
Yes, Paul A. DiSilvestro has studied treatments such as Cisplatin, Biospecimen Collection, Olaparib.
What is the best way to schedule an appointment with Paul A. DiSilvestro?
Apply for one of the trials that Paul A. DiSilvestro is conducting.
What is the office address of Paul A. DiSilvestro?
The office of Paul A. DiSilvestro is located at: Women and Infants Hospital, Providence, Rhode Island 02905 United States. This is the address for their practice at the Women and Infants Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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