Dr. Pankaj Arora, MD
Claim this profileUniversity of Alabama at Birmingham
Affiliated Hospitals
University Of Alabama At Birmingham
Clinical Trials Pankaj Arora, MD is currently running
Sacubitril-Valsartan
for High Blood Pressure
Obese individuals have a higher prevalence of nocturnal hypertension and non-dipping blood pressure (BP). These conditions are associated with an increased risk of cardiovascular (CV) events and death. Natriuretic Peptides (NPs) are hormones produced by the heart which directly regulate BP by causing dilation of blood vessels and by removing sodium and water from the body. NPs have a 24-hour day-night rhythm and this controls the day-night rhythm of BP as well. The NP-BP rhythm relationship is broken down in obese individuals. Obese individuals also have lower circulating NP levels. Lower circulating levels of NPs and elevated renin hormone (a part of the Renin-Angiotensin-Aldosterone System \[RAAS\]) at nighttime may contribute to the high nocturnal blood pressure in obese individuals which puts them at a higher risk of developing CV events. This current study seeks to determine the biological implications of chronopharmacology for synchronizing NP-RAAS-based blood pressure therapy with the physiological diurnal rhythms to restore the normal diurnal rhythm of blood pressure in obese individuals.
Recruiting
1 award
Phase 2 & 3
3 criteria
Sacubitril/Valsartan
for Metabolic Health in Black Individuals
This trial tests if sacubitril/valsartan can improve insulin sensitivity and energy use in Black individuals by increasing heart hormone levels. Black individuals are targeted because they often have lower levels of these hormones, leading to higher risks of diabetes. Valsartan has been studied for its potential to improve insulin sensitivity and β-cell function in various populations, including those with impaired glucose metabolism.
Recruiting
1 award
Phase 2
3 criteria
More about Pankaj Arora, MD
Clinical Trial Related
1 year of experience running clinical trials · Led 6 trials as a Principal Investigator · 4 Active Clinical Trials
Treatments Pankaj Arora, MD has experience with
- Sacubitril
- Valsartan
- Vericiguat
- Exercise Capacity VO2 Max Determination
- Exercise Challenge
- Glucose Challenge
Breakdown of trials Pankaj Arora, MD has run
Obesity
Cardiovascular Disease
Natriuretic Peptides
Energy Expenditure
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Pankaj Arora, MD specialize in?
Pankaj Arora, MD focuses on Obesity and Cardiovascular Disease. In particular, much of their work with Obesity has involved treating patients, or patients who are undergoing treatment.
Is Pankaj Arora, MD currently recruiting for clinical trials?
Yes, Pankaj Arora, MD is currently recruiting for 4 clinical trials in Birmingham Alabama. If you're interested in participating, you should apply.
Are there any treatments that Pankaj Arora, MD has studied deeply?
Yes, Pankaj Arora, MD has studied treatments such as Sacubitril, Valsartan, Vericiguat.
What is the best way to schedule an appointment with Pankaj Arora, MD?
Apply for one of the trials that Pankaj Arora, MD is conducting.
What is the office address of Pankaj Arora, MD?
The office of Pankaj Arora, MD is located at: University of Alabama at Birmingham, Birmingham, Alabama 35294 United States. This is the address for their practice at the University of Alabama at Birmingham.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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