Nobuko Hijiya, MD, Pediatric Hematology ...

Dr. Nobuko Hijiya, MD

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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center

Expert in Cancer
Expert in Brain Tumor
42 reported clinical trials
94 drugs studied

About Nobuko Hijiya, MD

Education:

  • Earned an MD (Doctor of Medicine) from an unspecified institution.

Experience:

  • Specializes in Pediatric Hematology-Oncology at NewYork-Presbyterian/Columbia University Medical Center.
  • Affiliated with the Herbert Irving Comprehensive Cancer Center.
  • Focuses on leukemias and lymphomas in children, adolescents, and young adults, with a particular interest in chronic myeloid leukemia (CML).
  • Actively involved in clinical research, particularly in studies on combination therapies for relapsed acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL).
  • Serves as a professor and section head of pediatric oncology, mentoring the next generation of medical professionals.

Area of expertise

1Cancer
Global Leader
Nobuko Hijiya, MD has run 15 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II
2Brain Tumor
Global Leader
Nobuko Hijiya, MD has run 12 trials for Brain Tumor. Some of their research focus areas include:
Stage I
Stage II
Stage IV

Affiliated Hospitals

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NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
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Columbia University Medical Center

Clinical Trials Nobuko Hijiya, MD is currently running

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Inotuzumab Ozogamicin

for Acute Lymphoblastic Leukemia

This phase III trial studies whether inotuzumab ozogamicin added to post-induction chemotherapy for patients with High-Risk B-cell Acute Lymphoblastic Leukemia (B-ALL) improves outcomes. This trial also studies the outcomes of patients with mixed phenotype acute leukemia (MPAL), and B-lymphoblastic lymphoma (B-LLy) when treated with ALL therapy without inotuzumab ozogamicin. Inotuzumab ozogamicin is a monoclonal antibody, called inotuzumab, linked to a type of chemotherapy called calicheamicin. Inotuzumab attaches to cancer cells in a targeted way and delivers calicheamicin to kill them. Other drugs used in the chemotherapy regimen, such as cyclophosphamide, cytarabine, dexamethasone, doxorubicin, daunorubicin, methotrexate, leucovorin, mercaptopurine, prednisone, thioguanine, vincristine, and pegaspargase or calaspargase pegol work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. This trial will also study the outcomes of patients with mixed phenotype acute leukemia (MPAL) and disseminated B lymphoblastic lymphoma (B-LLy) when treated with high-risk ALL chemotherapy. The overall goal of this study is to understand if adding inotuzumab ozogamicin to standard of care chemotherapy maintains or improves outcomes in High Risk B-cell Acute Lymphoblastic Leukemia (HR B-ALL). The first part of the study includes the first two phases of therapy: Induction and Consolidation. This part will collect information on the leukemia, as well as the effects of the initial treatment, to classify patients into post-consolidation treatment groups. On the second part of this study, patients with HR B-ALL will receive the remainder of the chemotherapy cycles (interim maintenance I, delayed intensification, interim maintenance II, maintenance), with some patients randomized to receive inotuzumab. The patients that receive inotuzumab will not receive part of delayed intensification. Other aims of this study include investigating whether treating both males and females with the same duration of chemotherapy maintains outcomes for males who have previously been treated for an additional year compared to girls, as well as to evaluate the best ways to help patients adhere to oral chemotherapy regimens. Finally, this study will be the first to track the outcomes of subjects with disseminated B-cell Lymphoblastic Leukemia (B-LLy) or Mixed Phenotype Acute Leukemia (MPAL) when treated with B-ALL chemotherapy.
Recruiting2 awards Phase 3
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Selinexor + Radiation

for Brain Cancer

This trial tests the safety and effectiveness of combining selinexor with radiation therapy in children and young adults with aggressive brain tumors. Selinexor is a drug that blocks a protein to stop cancer cells from growing. The study aims to find the best dose and see if this combination can shrink tumors.
Recruiting1 award Phase 1 & 21 criteria

More about Nobuko Hijiya, MD

Clinical Trial Related8 years of experience running clinical trials · Led 42 trials as a Principal Investigator · 18 Active Clinical Trials
Treatments Nobuko Hijiya, MD has experience with
  • Cyclophosphamide
  • Nivolumab
  • Radiation Therapy
  • Etoposide
  • Doxorubicin Hydrochloride
  • Vincristine

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