Dr. Nathan A. Pennell
Claim this profileCleveland Clinic Foundation
Expert in Lung Cancer
Expert in Non-Small Cell Lung Cancer
19 reported clinical trials
29 drugs studied
Area of expertise
1Lung Cancer
Global LeaderStage IV
Stage III
Stage II
2Non-Small Cell Lung Cancer
Global LeaderStage IV
Stage III
RET positive
Affiliated Hospitals
Clinical Trials Nathan A. Pennell is currently running
Osimertinib + Bevacizumab
for Lung Cancer
This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.
Recruiting2 awards Phase 331 criteria
Olomorasib
for Non-Small Cell Lung Cancer
The main purpose of this study is to assess if olomorasib in combination with pembrolizumab is more effective than the pembrolizumab and placebo combination in part A in participants with resected KRAS G12C-mutant NSCLC and to assess if olomorasib in combination with durvalumab is more effective than the durvalumab and placebo combination in part B in participants with unresectable KRAS G12C-mutant non-small cell lung cancer. The study may last up to 3 years for each participant.
Recruiting1 award Phase 38 criteria
More about Nathan A. Pennell
Clinical Trial Related3 years of experience running clinical trials · Led 19 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Nathan A. Pennell has experience with
- Pembrolizumab
- Docetaxel
- Carboplatin
- Pemetrexed Disodium
- Gemcitabine Hydrochloride
- Pemetrexed
Breakdown of trials Nathan A. Pennell has run
Lung Cancer
Non-Small Cell Lung Cancer
Solid Tumors
Colon Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Nathan A. Pennell specialize in?
Nathan A. Pennell focuses on Lung Cancer and Non-Small Cell Lung Cancer. In particular, much of their work with Lung Cancer has involved Stage IV patients, or patients who are Stage III.
Is Nathan A. Pennell currently recruiting for clinical trials?
Yes, Nathan A. Pennell is currently recruiting for 5 clinical trials in Cleveland Ohio. If you're interested in participating, you should apply.
Are there any treatments that Nathan A. Pennell has studied deeply?
Yes, Nathan A. Pennell has studied treatments such as Pembrolizumab, Docetaxel, Carboplatin.
What is the best way to schedule an appointment with Nathan A. Pennell?
Apply for one of the trials that Nathan A. Pennell is conducting.
What is the office address of Nathan A. Pennell?
The office of Nathan A. Pennell is located at: Cleveland Clinic Foundation, Cleveland, Ohio 44195 United States. This is the address for their practice at the Cleveland Clinic Foundation.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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