26 Participants Needed

Liquid Biopsy for Lung Cancer

NP
Overseen ByNathan Pennell, MD, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Case Comprehensive Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to see if using blood tests can help start treatment sooner for patients with newly diagnosed lung cancer. The goal is to reduce the time it takes to begin treatment.

Who Is on the Research Team?

Nathan Pennell, MD, PhD | Cleveland Clinic

Nathan A. Pennell

Principal Investigator

Cleveland Clinic, Case Comprehensive Cancer Center

Are You a Good Fit for This Trial?

This trial is for new patients with advanced nonsquamous non-small cell lung cancer (NSCLC) who plan to receive systemic therapy and are referred to the Cleveland Clinic Taussig Cancer Center without prior genetic testing results. It's not open to those who've had previous treatment or adequate molecular testing for their current NSCLC diagnosis.

Inclusion Criteria

I plan to get my treatment at Cleveland Clinic or another site but will follow up or share my records with Cleveland Clinic.
I have advanced non-squamous NSCLC and was referred to the Cleveland Clinic without prior genetic testing results.

Exclusion Criteria

I have received treatment for non-small cell lung cancer before.
You have already had the necessary genetic testing for your lung cancer diagnosis.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Liquid Biopsy Testing

Participants undergo liquid biopsy testing to detect cancer cells and actionable genetic markers

1 week
1 visit (in-person)

Treatment

Participants receive guideline-directed therapy based on liquid biopsy results

4 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Liquid biopsy
Trial Overview The study is examining whether liquid biopsies can speed up the start of treatment in advanced NSCLC patients. A liquid biopsy involves taking a blood sample to search for cancer cells, which may help in quicker decision-making regarding therapy.
How Is the Trial Designed?
1Treatment groups
Experimental Treatment
Group I: Liquid biopsyExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Case Comprehensive Cancer Center

Lead Sponsor

Trials
472
Recruited
33,400+
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