Dr. Michael Guy, MD
Claim this profileMiami Valley Hospital South
Area of expertise
Ovarian Cancer
Michael Guy, MD has run 9 trials for Ovarian Cancer. Some of their research focus areas include:
Endometrial Cancer
Michael Guy, MD has run 6 trials for Endometrial Cancer. Some of their research focus areas include:
Affiliated Hospitals
Miami Valley Hospital South
Miami Valley Hospital
Clinical Trials Michael Guy, MD is currently running
ACR-368
for Ovarian Cancer
This trial tests a new drug, ACR-368, alone or with a small dose of another drug, gemcitabine, in patients whose cancers don't respond to standard treatments. A special test helps decide which treatment might work best for each patient. Gemcitabine has been used with other drugs for various cancers, including pancreatic, lung, ovarian, and breast cancers.
Recruiting
1 award
Phase 2
10 criteria
Selumetinib + Olaparib
for Ovarian and Endometrial Cancer
This phase II ComboMATCH treatment trial compares selumetinib plus olaparib to selumetinib alone in women with endometrial or ovarian (fallopian tube and primary peritoneal) cancer that has come back (recurrent) or that remains despite treatment (persistent) and harbors a mutation in the RAS pathway. Selumetinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of olaparib to selumetinib could increase the percentage of tumors that shrink as well as lengthen the time that the tumors remain stable (without progression) as compared to selumetinib alone.
Recruiting
1 award
Phase 2
More about Michael Guy, MD
Clinical Trial Related
2 years of experience running clinical trials · Led 17 trials as a Principal Investigator · 7 Active Clinical Trials
Treatments Michael Guy, MD has experience with
- Paclitaxel
- Olaparib
- Letrozole
- Carboplatin
- Cediranib Maleate
- Durvalumab
Breakdown of trials Michael Guy, MD has run
Ovarian Cancer
- Selumetinib + Olaparib for Ovarian and Endometrial Cancer
- Upifitamab Rilsodotin Maintenance in Platinum-Sensitive Recurrent Ovarian Cancer (UP-NEXT)
- Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)
Endometrial Cancer
Fallopian Tube Cancer
Endometrial Adenocarcinoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Michael Guy, MD specialize in?
Michael Guy, MD focuses on Ovarian Cancer and Endometrial Cancer. In particular, much of their work with Ovarian Cancer has involved BRCA1 positive patients, or patients who are Stage IV.
Is Michael Guy, MD currently recruiting for clinical trials?
Yes, Michael Guy, MD is currently recruiting for 7 clinical trials in Centerville Ohio. If you're interested in participating, you should apply.
Are there any treatments that Michael Guy, MD has studied deeply?
Yes, Michael Guy, MD has studied treatments such as Paclitaxel, Olaparib, Letrozole.
What is the best way to schedule an appointment with Michael Guy, MD?
Apply for one of the trials that Michael Guy, MD is conducting.
What is the office address of Michael Guy, MD?
The office of Michael Guy, MD is located at: Miami Valley Hospital South, Centerville, Ohio 45459-447 United States. This is the address for their practice at the Miami Valley Hospital South.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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