Dr. Michael Cheng
Claim this profileDana Farber Cancer Institute
Studies Lung Cancer
Studies Skin Cancer
6 reported clinical trials
17 drugs studied
Area of expertise
1Lung Cancer
Stage III
Stage IV
Stage I
2Skin Cancer
metastatic
NUT gene translocation positive
NUT protein positive
Affiliated Hospitals
Clinical Trials Michael Cheng is currently running
Sigvotatug Vedotin vs Docetaxel
for Lung Cancer
This trial is testing a new drug, sigvotatug vedotin, against a standard drug, docetaxel, in patients with advanced lung cancer. The goal is to see if the new drug works better and to understand its side effects. Docetaxel (Taxotere) is a well-established chemotherapy agent used in the treatment of advanced non-small cell lung cancer (NSCLC), often after failure of first-line treatments.
Recruiting2 awards Phase 35 criteria
ZEN003694 + Chemotherapy
for Cancer
This phase I/II trial tests the safety, side effects, and best dose of a new combination of drugs, ZEN003694, cisplatin, and etoposide in treating patients with NUT carcinoma (phase I), and identifies whether this combination therapy works to shrink tumor in these patients (phase II). Another purpose of this study is to see whether there are any changes in patient's tumor or blood characteristics (e.g. genes, molecules, etc.) due to combination therapy. ZEN003694 inhibits the production of certain growth-promoting proteins and may prevent proliferation of tumor cells that use those proteins for their growth. Chemotherapy drugs, such as etoposide and cisplatin, work by stopping or slowing the growth of cancer cells. Combination therapy with ZEN003694, etoposide and cisplatin may be effective in treating patients with NUT carcinoma.
Recruiting1 award Phase 1 & 2
More about Michael Cheng
Clinical Trial Related5 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Michael Cheng has experience with
- Carboplatin
- Pembrolizumab
- Cisplatin
- Etoposide
- ZEN003694
- InVision
Breakdown of trials Michael Cheng has run
Lung Cancer
Skin Cancer
Non-Small Cell Lung Cancer
Squamous Cell Carcinoma
NUT Midline Carcinoma
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