Dr. Melissa A Burgess, MD - Pittsburgh ...

Dr. Melissa A. Burgess

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University of Pittsburgh Cancer Institute (UPCI)

Expert in Cancer
Studies Soft Tissue Sarcoma
24 reported clinical trials
42 drugs studied

About Melissa A. Burgess

Education:

  • Obtained a BS in Biochemistry & Molecular Biology and Chemistry from Dickinson College in 2005.

  • Earned an MD from Drexel University College of Medicine in 2009.

  • Completed Internal Medicine Residency at the University of Pittsburgh, UPMC (2009-2012).

  • Finished Hematology/Oncology Fellowship at the University of Pittsburgh, UPMC (2012-2015), serving as Chief in 2014.

Experience:

  • Serves as Assistant Professor of Medicine at the University of Pittsburgh School of Medicine.

  • Acts as a Clinical and Translational Investigator in Sarcoma, with a focus on clinical trials.

  • Holds the position of Local Principal Investigator for several clinical trials, including SARC 028 and CITN-09.

  • Specializes in the treatment of soft tissue and bone sarcoma patients at the Hillman Cancer Center.

Area of expertise

1

Cancer

Global Leader

Melissa A. Burgess has run 13 trials for Cancer. Some of their research focus areas include:

Stage IV
EWSR1/ATF1 positive
EWSR1/CREB1 positive
2

Soft Tissue Sarcoma

Melissa A. Burgess has run 10 trials for Soft Tissue Sarcoma. Some of their research focus areas include:

Stage IV
Stage III
EWSR1/ATF1 positive

Affiliated Hospitals

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University Of Pittsburgh Cancer Institute (UPCI)

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University Of Pittsburgh Medical Center

Clinical Trials Melissa A. Burgess is currently running

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Atezolizumab +/− Selinexor

for Sarcoma

This trial is testing if atezolizumab alone or with selinexor can shrink tumors in patients with a rare type of cancer called alveolar soft part sarcoma. Atezolizumab boosts the immune system to fight cancer, and selinexor stops cancer cells from growing. The goal is to see if these treatments work better than the usual care.

Recruiting

1 award

Phase 2

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Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

More about Melissa A. Burgess

Clinical Trial Related

5 years of experience running clinical trials · Led 24 trials as a Principal Investigator · 4 Active Clinical Trials

Treatments Melissa A. Burgess has experience with

  • Nivolumab
  • Atezolizumab
  • Doxorubicin
  • Dacarbazine
  • Placebo
  • Pembrolizumab

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