Dr. Matthew P. Deek, MD | New Brunswick ...

Dr. Matthew P Deek, MD

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Rutgers Cancer Institute of New Jersey

Studies Pancreatic Cancer
Studies Bone Cancer
6 reported clinical trials
12 drugs studied

Affiliated Hospitals

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Rutgers Cancer Institute Of New Jersey
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RWJBarnabas Health - Robert Wood Johnson University Hospital

Clinical Trials Matthew P Deek, MD is currently running

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Triapine + Targeted Radiation

for Neuroendocrine Cancer

This phase II trial compares the effect of adding triapine to lutetium Lu 177 dotatate versus lutetium Lu 177 dotatate alone (standard therapy) in shrinking tumors or slowing tumor growth in patients with neuroendocrine tumors that have spread from where they first started (primary site) to other places in the body (metastatic). Triapine may stop the growth of tumor cells by blocking some of the enzymes needed for deoxyribonucleic acid synthesis and cell growth. Lutetium Lu 177 dotatate is a radioactive drug. It binds to a protein called somatostatin receptor, which is found on some neuroendocrine tumor cells. Lutetium Lu 177 dotatate builds up in these cells and gives off radiation that may kill them. It is a type of radioconjugate and a type of somatostatin analog. Giving triapine in combination with lutetium Lu 177 dotatate may be more effective at shrinking tumors or slowing tumor growth in patients with metastatic neuroendocrine tumors than the standard therapy of lutetium Lu 177 dotatate alone.
Recruiting1 award Phase 2
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High-Dose Radiation

for Bone Metastases Pain

The investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 40-50% in painful non-spinal bone metastases. Additionally, the investigators hypothesize that utilizing a fractionation scheme with an escalated biologically equivalent dose (BED) will result in a higher proportion of participants responding to treatment, and will also lead to more durable responses. Furthermore, the investigators hypothesize that with dose escalation to 40-50 Gy in ten fractions, the complete pain response rate at one month can be increased to 35-45% in painful non-bone metastases
Recruiting1 award Phase 211 criteria

More about Matthew P Deek, MD

Clinical Trial Related2 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 4 Active Clinical Trials
Treatments Matthew P Deek, MD has experience with
  • EXTERNAL BEAM RADIATION
  • AN0025
  • Capecitabine
  • Fluorouracil
  • Intensity-Modulated Radiation Therapy
  • Mitomycin

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