Dr. John R. Mansueti
Claim this profileTidalHealth Richard A Henson Cancer Institute
Affiliated Hospitals
TidalHealth Richard A Henson Cancer Institute
TidalHealth Peninsula Regional
Clinical Trials John R. Mansueti is currently running
High-Dose Radiation + Chemotherapy and Immunotherapy
for Non-Small Cell Lung Cancer
This trial tests whether adding a precise form of radiation therapy to the usual treatment improves outcomes for patients with advanced lung cancer that can't be operated on. The goal is to see if this combination helps patients live longer and prevents cancer from worsening. This form of radiation therapy has shown promise in improving survival rates in patients with various stages of lung cancer.
Recruiting
2 awards
Phase 3
14 criteria
Hormone Therapy + Radiation
for Prostate Cancer
This phase III trial uses the Decipher risk score to guide therapy selection. Decipher score is based on the activity of 22 genes in prostate tumor and may predict how likely it is for recurrent prostate cancer to spread (metastasize) to other parts of the body. Decipher score in this study is used for patient selection and the two variations of treatment to be studied: intensification for higher Decipher score or de-intensification for low Decipher score. Patients with higher Decipher risk score will be assigned to the part of the study that compares the use of 6 months of the usual treatment (hormone therapy and radiation treatment) to the use of darolutamide plus the usual treatment (intensification). The purpose of this section of the study is to determine whether the additional drug can reduce the chance of cancer coming back and spreading in patients with higher Decipher score. The addition of darolutamide to the usual treatment may better control the cancer and prevent it from spreading. Alternatively, patients with low Decipher risk score will be assigned to the part of the study that compares the use of radiation treatment alone (de-intensification) to the usual approach (6 months of hormone therapy plus radiation). The purpose of this part of the study is to determine if radiation treatment alone is as effective compared to the usual treatment without affecting the chance of tumor coming back in patients with low Decipher score prostate cancer. Radiation therapy uses high energy to kill tumor cells and reduce the tumor size. Hormone therapy drugs such as darolutamide suppress or block the production or action of male hormones that play role in prostate cancer development. Effect of radiation treatment alone in patients with low Decipher score prostate cancer could be the same as the usual approach in stabilizing prostate cancer and preventing it from spreading, while avoiding the side effects associated with hormonal therapy.
Recruiting
2 awards
Phase 3
1 criteria
More about John R. Mansueti
Clinical Trial Related
10 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments John R. Mansueti has experience with
- Flutamide
- Docetaxel
- External Beam Radiation Therapy
- Goserelin Acetate
- Nilutamide
- Intensity-Modulated Radiation Therapy (IMRT)
Breakdown of trials John R. Mansueti has run
Prostate Cancer
Prostate Adenocarcinoma
Lung Cancer
Small Cell Lung Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does John R. Mansueti specialize in?
John R. Mansueti focuses on Prostate Cancer and Prostate Adenocarcinoma. In particular, much of their work with Prostate Cancer has involved treating patients, or patients who are undergoing treatment.
Is John R. Mansueti currently recruiting for clinical trials?
Yes, John R. Mansueti is currently recruiting for 2 clinical trials in Ocean Pines Maryland. If you're interested in participating, you should apply.
Are there any treatments that John R. Mansueti has studied deeply?
Yes, John R. Mansueti has studied treatments such as Flutamide, Docetaxel, External Beam Radiation Therapy.
What is the best way to schedule an appointment with John R. Mansueti?
Apply for one of the trials that John R. Mansueti is conducting.
What is the office address of John R. Mansueti?
The office of John R. Mansueti is located at: TidalHealth Richard A Henson Cancer Institute, Ocean Pines, Maryland 21811 United States. This is the address for their practice at the TidalHealth Richard A Henson Cancer Institute.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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