Dr. John Fahy | UCSF Health

Dr. John Fahy, MD, MS

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UCSF Airway Clinical Research Center

Studies Asthma
Studies Chronic Obstructive Pulmonary Disease
5 reported clinical trials
12 drugs studied

Affiliated Hospitals

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UCSF Airway Clinical Research Center
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University Of California, San Francisco

Clinical Trials John Fahy, MD, MS is currently running

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Positive Airway Pressure + NAC

for COPD

The goal of this clinical trial is to determine if positive pressure during inspiration will improve penetration of aerosolized N-Acetylcysteine (NAC) into airway mucus plugs in the lungs of patients with asthma or Chronic Obstructive Pulmonary Disease (COPD). The main questions it aims to answer are: * Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on mucus plug burden in the lungs than delivery of NAC without positive pressure. * Does delivery of aerosolized NAC with positive inspiratory pressure have a greater effect on lung function than delivery of NAC without positive pressure. Participants will be assigned (in a single blind design) to the NAC via jet nebulizer group or the NAC via AeroEclipse-VersaPAP nebulizer group. Participants will each complete 5 treatment visits over the course of 30 days. Each treatment visit will consist of two treatments of a 10% NAC (3 mL) and 2.5 mg albuterol (0.5mL) inhalation solution separated by 4 hours, via the nebulization method specific to their group.
Recruiting3 awards Phase 415 criteria
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Metabolic Dysfunction and Mucus Plugging

for Asthma

This is a single-center study of 80 subjects with asthma including those with obesity and metabolic dysfunction (MD), those with obesity and without metabolic dysfunction, those with severe asthma and mucus plugging and those with severe asthma and without mucus plugging. Screening data will be reviewed to determine participant eligibility. Participants who meet all inclusion criteria will participate in a cardiopulmonary exercise testing (CPET) visit to compare lung function markers and change in oxygen saturation between obese patients with and without MD and severe asthma patients with and without mucus plugging.
Recruiting1 award N/A6 criteria

More about John Fahy, MD, MS

Clinical Trial Related3 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments John Fahy, MD, MS has experience with
  • Broncho-Vaxom
  • Cavosonstat
  • Clazakizumab
  • Imatinib Mesylate
  • Itacitinib
  • MCT

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