John A. Charlson, MD | Froedtert & the ...

Dr. John Charlson, MD

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Medical College of Wisconsin

Studies Cancer
Studies Soft Tissue Sarcoma
15 reported clinical trials
24 drugs studied

Area of expertise

1Cancer
John Charlson, MD has run 9 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage III
FOXO1 fusion negative
2Soft Tissue Sarcoma
John Charlson, MD has run 7 trials for Soft Tissue Sarcoma. Some of their research focus areas include:
Stage IV
Stage III
p16 positive

Affiliated Hospitals

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Medical College Of Wisconsin
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Froedtert Hospital & The Medical College Of Wisconsin

Clinical Trials John Charlson, MD is currently running

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ADI-PEG 20 + Chemotherapy

for Leiomyosarcoma

To compare the efficacy and safety in subjects with advanced or metastatic LMS previously treated with an anthracycline.
Recruiting1 award Phase 310 criteria
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Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.
Recruiting2 awards Phase 310 criteria

More about John Charlson, MD

Clinical Trial Related5 years of experience running clinical trials · Led 15 trials as a Principal Investigator · 4 Active Clinical Trials
Treatments John Charlson, MD has experience with
  • Temozolomide
  • Nivolumab
  • Cyclophosphamide
  • Pembrolizumab
  • Abemaciclib
  • Cabozantinib

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