Dr. Jeffrey E. Rubnitz, MD, PhD
Claim this profileSt. Jude Children's Research Hospital
Area of expertise
Acute Myelogenous Leukemia
Jeffrey E. Rubnitz, MD, PhD has run 10 trials for Acute Myelogenous Leukemia. Some of their research focus areas include:
Acute Myeloid Leukemia
Jeffrey E. Rubnitz, MD, PhD has run 9 trials for Acute Myeloid Leukemia. Some of their research focus areas include:
Affiliated Hospitals
St Jude Children's Research Hospital
Saint Jude Children's Research Hospital
Clinical Trials Jeffrey E. Rubnitz, MD, PhD is currently running
Talazoparib + Chemotherapy
for Acute Myeloid Leukemia
This trial is testing the safety of using talazoparib with standard chemotherapy in cancer patients. Talazoparib works by stopping cancer cells from repairing themselves, which could make chemotherapy more effective. The study aims to find the safest dose combination and see if this approach helps patients. Talazoparib is FDA approved for certain types of breast cancer that have spread and were previously treated with chemotherapy.
Recruiting
1 award
Phase 1
19 criteria
Revumenib + Chemotherapy
for Acute Myeloid Leukemia
This is a research study to find out if adding a new study drug called revumenib to commonly used chemotherapy drugs is safe and if they have beneficial effects in treating patients with acute myeloid leukemia (AML) or acute leukemia of ambiguous lineage (ALAL) that did not go into remission after treatment (refractory) or has come back after treatment (relapsed), and to determine the total dose of the 3-drug combination of revumenib, azacitidine and venetoclax that can be given safely in participants also taking an anti-fungal drug. Primary Objective * To determine the safety and tolerability of revumenib + azacitidine + venetoclax in pediatric patients with relapsed or refractory AML or ALAL. Secondary Objectives * Describe the rates of complete remission (CR), complete remission with incomplete count recovery (CRi), and overall survival for patients treated with revumenib + azacitidine + venetoclax at the recommended phase 2 dose (RP2D).
Recruiting
1 award
Phase 1
10 criteria
More about Jeffrey E. Rubnitz, MD, PhD
Clinical Trial Related
6 years of experience running clinical trials · Led 13 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Jeffrey E. Rubnitz, MD, PhD has experience with
- Cytarabine
- Venetoclax
- Azacitidine
- Fludarabine
- Decitabine
- Selinexor
Breakdown of trials Jeffrey E. Rubnitz, MD, PhD has run
Acute Myelogenous Leukemia
Acute Myeloid Leukemia
Leukemia
Biphenotypic Leukemia
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Jeffrey E. Rubnitz, MD, PhD specialize in?
Jeffrey E. Rubnitz, MD, PhD focuses on Acute Myelogenous Leukemia and Acute Myeloid Leukemia. In particular, much of their work with Acute Myelogenous Leukemia has involved t(9;11) positive patients, or patients who are inv(16) positive.
Is Jeffrey E. Rubnitz, MD, PhD currently recruiting for clinical trials?
Yes, Jeffrey E. Rubnitz, MD, PhD is currently recruiting for 3 clinical trials in Memphis Tennessee. If you're interested in participating, you should apply.
Are there any treatments that Jeffrey E. Rubnitz, MD, PhD has studied deeply?
Yes, Jeffrey E. Rubnitz, MD, PhD has studied treatments such as Cytarabine, Venetoclax, Azacitidine.
What is the best way to schedule an appointment with Jeffrey E. Rubnitz, MD, PhD?
Apply for one of the trials that Jeffrey E. Rubnitz, MD, PhD is conducting.
What is the office address of Jeffrey E. Rubnitz, MD, PhD?
The office of Jeffrey E. Rubnitz, MD, PhD is located at: St. Jude Children's Research Hospital, Memphis, Tennessee 38105 United States. This is the address for their practice at the St. Jude Children's Research Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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