Jay W. Carlson, DO, MS – Cancer ...

Dr. Jay W Carlson

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Mercy Hospital Saint Louis

Expert in Cancer
Expert in Breast Cancer
219 reported clinical trials
295 drugs studied

Area of expertise

1

Cancer

Global Leader

Jay W Carlson has run 36 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage III
2

Breast Cancer

Global Leader

Jay W Carlson has run 36 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
HER2 positive
Stage II

Affiliated Hospitals

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Mercy Hospital Saint Louis

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Mercy Hospital Springfield

Clinical Trials Jay W Carlson is currently running

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Chemotherapy + Immunotherapy

for Esophageal and Gastric Cancer

This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.

Recruiting

2 awards

Phase 3

2 criteria

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Chemotherapy + Hormone Therapy

for Breast Cancer

This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.

Recruiting

2 awards

Phase 3

19 criteria

More about Jay W Carlson

Clinical Trial Related

7 years of experience running clinical trials · Led 219 trials as a Principal Investigator · 91 Active Clinical Trials

Treatments Jay W Carlson has experience with

  • Nivolumab
  • Pembrolizumab
  • Carboplatin
  • Cisplatin
  • Paclitaxel
  • Atezolizumab

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